Abstract
Contrary to the situation in animal systems, plant shape and size are predominantly determined by developmental programs that govern the timely initiation and outgrowth of meristems. In plants, meristematic zones almost exclusively constitute the regions of dividing cells. The role of mitotic cell division in morphogenetic and developmental processes has been the subject of intense debate, but the present view seems to acknowledge the importance of proper cell division regulation for the correct elaboration and execution of developmental programs (29)
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Breyne P, Dreesen R, Vandepoele K, De Veylder L, Van Breusegem F, Callewaert L, Rombauts S, Raes J, Cannoot B, Engler G, Inze D, Zabeau M (2002) Transcriptome analysis during cell division in plants. Proc Natl Acad Sci U S A 99: 14825-14830
Bryant J, Francis D (2001) Plant growth regulators and the control of S-phase. In D. Francis, ed The plant cell cycle and its interfaces. Sheffield Academic Press; CRC Press, Sheffield, UK; Boca Raton, FL, pp 43-55
Brzobohaty B, Moore I, Kristoffersen P, Bako L, Campos N, Schell J, Palme K (1993) Figure 9. Tentative model for the action of zeatin at G2/M transtion in the tobacco BY-2 cell culture. Zeatin and auxin cooperate to up-regulate CDKA and cyclin B expression. The activity of the cyclin/CDK complex is enhanced by a stimulatory phosphorylation on the CDK moiety at Thr170 and is inhibited by a phosphorylation at Tyr15 (and possibly also Thr14) by Wee1-like kinase(s). Zeatin counteracts the Wee1 induced inhibition through the action of a cdc25-like phosphatase activity that removes the inhibitory phosphorylation(s) (amino acid numbering according to tobacco). Release of active cytokinin by a beta-glucosidase localized to the maize root meristem. Science 262: 1051-4
Carimi F, Zottini M, Formentin E, Terzi M, Lo Schiavo F (2003) Cytokinins: new apoptotic inducers in plants. Planta 216: 413-421
Crowell DN, Salaz MS (1992) Inhibition of growth of cultured tobacco cells at low concentrations of lovastatin is reversed by cytokinin. Plant Physiol 100: 2090-2095
Das NK, Patau K, Skoog F (1956) Initiation and cell division by kinetin and indoleacetic acid in excised tobacco pith tissue. Physiol Plant 9: 640-651
de O. Manes C, Van Montagu M, Prinsen E, Goethals K, Holsters M (2001) De novo cortical cell division triggered by the phytopathogen Rhodococcus fascians in tobacco. Mol Plant Microbe Interact 14: 189-195
Dewitte W, Chiappetta A, Azmi A, Witters E, Strnad M, Rembur J, Noin M, Chriqui D, Van Onckelen H (1999) Dynamics of cytokinins in apical shoot meristems of a dayneutral tobacco during floral transition and flower formation. Plant Physiol 119: 111-122
Dewitte W, Murray JAH (2003) The plant cell cycle. Annu Rev Plant Biol 54: 235-264
Dewitte W, Van Onckelen H (2001) Probing the distribution of plant hormones by immunocytochemistry. Plant Growth Regul 33: 67-74
Dobrev P, Motyka V, Gaudinova A, Malbeck J, Travnickova A, Kaminek M, Vankova R (2002) Transient accumulation of cis- and trans-zeatin type cytokinins and its relation to cytokinin oxidase activity during cell cycle of synchronized tobacco BY-2 cells. Plant Physiol Biochem 40: 333-337
Estruch JJ, Granell A, Hansen G, Prinsen E, Redig P, Van Onckelen H, Schwarz- Sommer Z, Sommer H, Spena A (1993) Floral development and expression of floral homeotic genes are influenced by cytokinins. Plant J 4: 379-384
Francis D, Sorrell DA (2001) The interface between the cell cycle and plant growth regulators: a mini review. Plant Growth Regul 33: 1-12
Frank M, Guivarc'h A, Krupkova E, Lorenz-Meyer I, Chriqui D, Schmulling T (2002) TUMOROUS SHOOT DEVELOPMENT (TSD) genes are required for co-ordinated plant shoot development. Plant J 29: 73-85
Glab N, Labidi B, Qin LX, Trehin C, Bergounioux C, Meijer L (1994) Olomoucine, an inhibitor of the cdc2/cdk2 kinases activity, blocks plant cells at the G1 to S and G2 to M cell cycle transitions. FEBS Lett 353: 207-211
Helliwell CA, Chin-Atkins AN, Wilson IW, Chapple R, Dennis ES, Chaudhury A (2001) The Arabidopsis AMP1 gene encodes a putative glutamate carboxypeptidase. Plant Cell 13: 2115-2125
Hemerly AS, Ferreira P, de Almeida Engler J, Van Montagu M, Engler G, Inze D (1993) cdc2a expression in Arabidopsis is linked with competence for cell division. Plant Cell 5: 1711-1723
Hemmerlin A, Bach TJ (1998) Effects of mevinolin on cell cycle progression and viability of tobacco BY-2 cells. Plant J 14: 65-74
Houssa C, Bernier G, Pieltain A, Kinet JM, Jacqmard A (1994) Activation of latent DNA-replication origins - a universal effect of cytokinins. Planta 193: 247-250
Inoue T, Higuchi M, Hashimoto Y, Seki M, Kobayashi M, Kato T, Tabata S, Shinozaki K, Kakimoto T (2001) Identification of CRE1 as a cytokinin receptor from Arabidopsis. Nature 409: 1060-1063
Ivanova M, Rost TL (1997) Cytokinins and the plant cell cycle: Problems and pitfalls of proving their function. In JA Bryant, D Chiatante, eds Plant cell proliferation and its regulation in growth and development. John Wiley & Sons, Chichester, pp 45-57
John PCL (1998) Cytokinin stimulation of cell division: essential signal transduction is via Cdc25 phosphatase. J Exp Bot 49 (suppl.): 91
Laureys F, Dewitte W, Witters E, Van Montagu M, Inze D, Van Onckelen H (1998) Zeatin is indispensable for the G2-M transition in tobacco BY-2 cells. FEBS Lett 426: 29-32
Laureys F, Smets R, Lenjou M, Van Bockstaele D, Inze D, Van Onckelen H (1999) A low content in zeatin type cytokinins is not restrictive for the occurrence of G1/S transition in tobacco BY-2 cells. FEBS Lett 460: 123-128
25. Letham DS (1963) Zeatin, a factor inducing cell division from Zea mays. Life Sci 8:
Mader JC, Hanke DE (1996) Immunocytochemical study of cell cycle control by cytokinin in cultured soybean cells. J Plant Growth Regul 15: 95-102
Magyar Z, Atanassova A, De Veylder L, Rombauts S, Inze D (2000) Characterization of two distinct DP-related genes from Arabidopsis thaliana. FEBS Lett 486: 79-87
Mähönen AP, Bonke M, Kauppinen L, Riikonen M, Benfey PN, Helariutta Y (2000) A novel two-component hybrid molecule regulates vascular morphogenesis of the Arabidopsis root. Genes Dev 14: 2938-2943
Meijer M, Murray JA (2001) Cell cycle controls and the development of plant form. Curr Opin Plant Biol 4: 44-49
Menges M, Hennig L, Gruissem W, Murray JA (2002) Cell cycle-regulated gene expression in Arabidopsis. J Biol Chem 277: 41987-42002
Menges M, Murray JA (2002) Synchronous Arabidopsis suspension cultures for analysis of cell-cycle gene activity. Plant J 30: 203-212
Miller CO, Skoog F, von Saltza MH, Strong FM (1955) Kinetin, a cell division factor from deoxyribonucleic acid. J Amer Chem Soc 77: 1329-1334
Mironov V, De Veylder L, Van Montagu M, Inze D (1999) Cyclin-dependent kinases and cell division in plants- the nexus. Plant Cell 11: 509-522
Mlejnek P, Procházka S (2002) Activation of caspase-like proteases and induction of apoptosis by isopentenyladenosine in tobacco BY-2 cells. Planta 215: 158-166
Murray JAH, Doonan J, Riou-Khamlichi C, Meijer M, Oakenfull EA (2001) G1 cyclins, cytokinins and the regulation of the G1/S transition. In D. Francis, ed The plant cell cycle and its interfaces. Sheffield Academic Press; CRC Press, Sheffield, UK; Boca Raton, FL, pp 19-41
Nagata T, Kumagai F (1999) Plant cell biology through the window of the highly synchronized tobacco BY-2 cell line. Methods Cell Sci 21: 123-127
Nagata T, Nemoto Y, Hasezawa S (1992) Tobacco BY-2 cell line as the 'HeLa' cell in the cell biology of higher plants. Int Rev Cytol 132: 1-30
Nakagami H, Kawamura K, Sugisaka K, Sekine M, Shinmyo A (2002) Phosphorylation of retinoblastoma-related protein by the cyclin D/cyclin-dependent kinase complex is activated at the G1/S-phase transition in tobacco. Plant Cell 14: 1847-1857
Nishinari N, Syono K (1986) Induction of cell division synchrony and variation of cytokinin contents through the cell cycle in tobacco cultured cells. Plant Cell Physiol 27: 147-153
Papon N, Clastre M, Gantet P, Rideau M, Chenieux JC, Creche J (2003) Inhibition of the plant cytokinin transduction pathway by bacterial histidine kinase inhibitors in Catharanthus roseus cell cultures. FEBS Lett 537: 101-105
Planchais S, Glab N, Inze D, Bergounioux C (2000) Chemical inhibitors: a tool for plant cell cycle studies. FEBS Lett 476: 78-83
Planchais S, Glab N, Trehin C, Perennes C, Bureau JM, Meijer L, Bergounioux C (1997) Roscovitine, a novel cyclin-dependent kinase inhibitor, characterizes restriction point and G2/M transition in tobacco BY-2 cell suspension. Plant J 12: 191-202
Prinsen E, Van Dongen W, Esmans EL, Van Onckelen HA (1998) Micro and capillary liquid chromatography tandem mass spectrometry: a new dimension in phytohormone research. J Chromatogr A 826: 25-37
Redig P, Schmulling T, Van Onckelen H (1996) Analysis of cytokinin metabolism in ipt transgenic tobacco by Liquid Chromatography-Tandem Mass Spectrometry. Plant Physiol 112: 141-148
Redig P, Shaul O, Inze D, Van Montagu M, Van Onckelen H (1996) Levels of endogenous cytokinins, indole-3-acetic acid and abscisic acid during the cell cycle of synchronized tobacco BY-2 cells. FEBS Lett 391: 175-180
Riou-Khamlichi C, Huntley R, Jacqmard A, Murray JAH (1999) Cytokinin activation of Arabidopsis cell division through a D-type cyclin. Science 283: 1541-1544
Sakai H, Honma T, Aoyama T, Sato S, Kato T, Tabata S, Oka A (2001) ARR1, a transcription factor for genes immediately responsive to cytokinins. Science 294: 1519-1521
Schulze-Gahmen U, Brandsen J, Jones HD, Morgan DO, Meijer L, Vesely J, Kim SH (1995) Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine. Proteins 22: 378-391
Skoog F, Miller CO (1957) Chemical regulation of growth and organ formation in plant tissues cultured in vitro. Symp Soc Exp Biol 11: 118-131
Smalle J, Kurepa J, Yang P, Babiychuk E, Kushnir S, Durski A, Vierstra RD (2002) Cytokinin growth responses in Arabidopsis involve the 26S proteasome subunit RPN12. Plant Cell 14: 17-32
Sorrell DA, Combettes B, Chaubet-Gigot N, Gigot C, Murray JA (1999) Distinct cyclin D genes show mitotic accumulation or constant levels of transcripts in tobacco Bright Yellow-2 cells. Plant Physiol 119: 343-352
Sorrell DA, Marchbank A, McMahon K, Dickinson JR, Rogers HJ, Francis D (2002) A WEE1 homologue from Arabidopsis thaliana. Planta 215: 518-522
Stals H, Inze D (2001) When plant cells decide to divide. Trends Plant Sci 6: 359-364
Suzuki T, Miwa K, Ishikawa K, Yamada H, Aiba H, Mizuno T (2001) The Arabidopsis sensor His-kinase, AHK4, can respond to cytokinins. Plant Cell Physiol 42: 107-113
Temmerman W, Ritsema T, Simon-Mateo C, Van Montagu M, Mironov V, Inze D, Goethals K, Holsters M (2001) The fas locus of the phytopathogen Rhodococcus fascians affects mitosis of tobacco BY-2 cells. FEBS Lett 492: 127-132
The Arabidopsis Genome Initiative (2000) Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature 408: 796-815
Vermeulen K, Strnad M, Havlicek L, Van Onckelen H, Lenjou M, Nijs G, Van Bockstaele DR, Berneman ZN (2002) Plant cytokinin analogues with inhibitory activity on cyclin-dependent kinases exert their antiproliferative effect through induction of apoptosis initiated by the mitochondrial pathway: determination by a multiparametric flow cytometric analysis. Exp Hematol 30: 1107-1114
Vittorioso P, Cowling R, Faure JD, Caboche M, Bellini C (1998) Mutation in the Arabidopsis PASTICCINO1 gene, which encodes a new FK506- binding protein-like protein, has a dramatic effect on plant development. Mol Cell Biol 18: 3034-43
Witters E, Vanhoutte K, Dewitte W, Machackova I, Benkova E, Van Dongen W, Esmans EL, Van Onckelen HA (1999) Analysis of cyclic nucleotides and cytokinins in minute plant samples using phase-system switching capillary electrospray-liquid chromatography-tandem mass spectrometry. Phytochem Anal 10: 143-151
Yamada H, Suzuki T, Terada K, Takei K, Ishikawa K, Miwa K, Yamashino T, Mizuno T (2001) The Arabidopsis AHK4 histidine kinase is a cytokinin-binding receptor that transduces cytokinin signals across the membrane. Plant Cell Physiol 42: 1017-1023
Yang SW, Jin E, Chung IK, Kim WT (2002) Cell cycle-dependent regulation of telomerase activity by auxin, abscisic acid and protein phosphorylation in tobacco BY-2 suspension culture cells. Plant J 29: 617-626
Zhang K, Letham DS, John PC (1996) Cytokinin controls the cell cycle at mitosis by stimulating the tyrosine dephosphorylation and activation of p34cdc2-like H1 histone kinase. Planta 200: 2-12
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer Science+Business Media B.V.
About this chapter
Cite this chapter
Roef, L., Van Onckelen, H. (2010). Cytokinin Regulation of the Cell Division Cycle. In: Davies, P.J. (eds) Plant Hormones. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-2686-7_12
Download citation
DOI: https://doi.org/10.1007/978-1-4020-2686-7_12
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-2684-3
Online ISBN: 978-1-4020-2686-7
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)