Biosynthesis of the tetrapyrrole ring system
The pathways for the biosynthesis of chlorophyll and respiratory pigments of the heme type make use of the same series of reactions up to the protoporphyrin stage. Judicious use of isotopes, of cell preparations catalyzing some of the reactions involved and degradation techniques specially devised for the task, have allowed the brilliant elucidation of the pathway by several groups of workers, among which David Shemin occupies the main place.
KeywordsCodon NADPH Methionine Transferrin Pyrrole
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