Biosynthesis of the amino acids of the glutamic acid family and its regulation

  • Georges N. Cohen


This reaction is carried out by an enzyme, glutamine synthetase, whose occurrence is not restricted to microorganisms. It is esential not only for the synthesis of glutamine, a building block of proteins. Glutamine contributes also through its amide group to the synthesis of many nitrogen containing substances; in addition, it is an obligatory intermediate in ammonia assimilation in ammonia-limited media.


Glutamine Synthetase Glutamine Synthetase Activity Proline Biosynthesis Carbamyl Phosphate Arginine Biosynthesis 
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Copyright information

© Springer Science+Business Media Dordrecht 2004

Authors and Affiliations

  • Georges N. Cohen
    • 1
    • 2
  1. 1.Centre National de la Recherche ScientifiqueParisFrance
  2. 2.Institut PasteurParisFrance

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