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Genetic Neurological and Psychiatric Diseases

  • Chapter
Genetic Disorders of the Indian Subcontinent

Abstract

Recent advances in molecular biology have ushered in a new era of Neurology. In recent years, more and more genetic diseases have been diagnosed based on molecular tests. As infectious diseases of the nervous system such as poliomyelitis decrease in a given population, a larger proportion of neurological disorder encountered have a genetic basis. In a review of referral patterns to tertiary genetic centers in India, Verma et al (2003) found that a high percentage of referrals to molecular diagnostic laboratories are for neurological conditions. Duchenne muscular dystrophy (12.5%), Fragile X syndrome (10.3%), spinal muscular atrophy (8.9%), triplet repeat disorders-spinocerebellar ataxias, Huntington disease and Friedreich ataxia (4.6%) and mitochondrial disorders (2.9%) account for about 40% of all referrals.

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Authors
  1. Dhavendra Kumar
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  2. Michael A. Patton
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  3. Ajith Kumar
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Editors and Affiliations

  1. Department of Clinical Genetics, The Churchill Hospital, Oxford Radcliffe Hospitals NHS Trust, Headington, Oxford, UK

    Dhavendra Kumar

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Kumar, D., Patton, M.A., Kumar, A. (2004). Genetic Neurological and Psychiatric Diseases. In: Kumar, D. (eds) Genetic Disorders of the Indian Subcontinent. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-2231-9_16

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  • DOI: https://doi.org/10.1007/978-1-4020-2231-9_16

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