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Disorders of Haemostasis and Thrombosis

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Genetic Disorders of the Indian Subcontinent
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Abstract

The incidence of hereditary bleeding and thrombotic disorders in the developed world is well known. However, majority of the patients live, and are cared for, in developing countries, where data on incidence is limited (Nathwani and Tuddenham, 1992). Some haemostasis and thrombosis centres in the UK serve populations with large south Asian groups. The nature and incidence of haemostasis disorder seen in these groups will partly reflect those in the country of origin but other factors, such as the degree of consanguinity, may also be important.

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References

  • Bauer K, Goodnight S, Ridker P (1998) Hypercoaguable states -Translation of risk factors to clinical practice. Education Programme, American Society of Haematology, 255–271

    Google Scholar 

  • Bolton-Maggs P (1998) The management of factor XI deficiency. Haemophilia 4: 683–688

    Article  PubMed  CAS  Google Scholar 

  • Census-UK (2001) http://www.statistics.gov.uk/census2001/profiles/00cx.asp#ethnic.

    Google Scholar 

  • Census-UK (2001) http://www.statistics.gov.uk/census2001/profiles/00cx.asp#ethnic Chowdhury MR, Kabra M, Menon PSN (2001) Factor IX gene polymorphisms in India population. Am J Haematol 68:246–248

    Article  CAS  Google Scholar 

  • Ginsburg D, Nichols WC, Zivelin A, Kaufman RJ, Seligsohn U (1998) Combined factors V and VIII deficiency–the solution. Haemophilia 4: 677–682

    Article  PubMed  CAS  Google Scholar 

  • Kar A, Potnis-Lele (2001) Descriptive Epidemiology of Haemophilia in Maharashtra, India. Haemophilia Nov 7: 561–567

    Article  CAS  Google Scholar 

  • Karimi M, Yarmohammadi H, Ardeshiri R (2002) Inherited coagulation disorder in southern Iran. Haemophilia 8 (6): 740–744

    Article  PubMed  CAS  Google Scholar 

  • Kouides PA, Kulzer L (2001) Prophylactic treatment of severe factor X deficiency with prothrombin complex concentrate. Haemophilia 7: 220–223

    Article  PubMed  CAS  Google Scholar 

  • Macheta MP, Minford AM, Parapia LA (1997) Incidence of hereditary bleeding disorders in Bradford, UK: variation with ethnic group. Haemophilia 3: 292–294

    Article  Google Scholar 

  • Martin PG,Redman C, Keeling DM (1998) Novel identifications of homozygous factor V Leiden mutation in three UK Asian sisters. Blood Coagulation and Fibrinolysis 9: 295–296

    Article  PubMed  CAS  Google Scholar 

  • Nair S, Ghosh K, Kulkarni B, Shetty S, Mohanty D (2002) Glanzmann’s Thrombasthenia: updated. Platelets 13: 387–393

    Article  PubMed  CAS  Google Scholar 

  • Nathwani AC, Tuddenham (1992) Epidemiology of coagulation disorders. Clinical Haematology 6 (5.2): 383–439

    Google Scholar 

  • Newton LJ, Krishnan A, Parapia L (1999) Born to Clot: The European Burden. British Journal of Haematology 107 (1): 213–215

    Article  PubMed  CAS  Google Scholar 

  • Peyvandi (2000), Rare coagulation disorders, MD Thesis

    Google Scholar 

  • Peyvandi F, Manucci PM (1999) Rare coagulation disorders. Thromb Haemost 82 (4): 1207–14

    PubMed  CAS  Google Scholar 

  • Rees DC, Chapman NH, Webster TM, Guerreiro JF, Rochette J, Clegg JB (1999) Born to clot: The European Burden. British Journal of Haematology 105: 564–566

    Article  PubMed  CAS  Google Scholar 

  • Rees DC, Cox M, Clegg JB (1995) World distribution of Factor V Leiden. Lancet Vol 346 Oct 28, 1133–1134

    Article  PubMed  CAS  Google Scholar 

  • Saxena, R S, Mohanty D, Srivastava A, Choudry VP, Kotwal J (1999) Pathogenetic factors underlying juvenile deep vein thrombosis (DVT) in Indians. European Journal Haematology 63: 26–28

    Article  CAS  Google Scholar 

  • United Kingdom Haemophilia Centre Doctors Organization (UKHCDO) (2003) Guidelines on the selection and use of therapeutic products to treat haemophilia and other bleeding disorders. Haemophilia 9: 1–23.

    Article  Google Scholar 

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© 2004 Springer Science+Business Media Dordrecht

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Parapia, L. (2004). Disorders of Haemostasis and Thrombosis. In: Kumar, D. (eds) Genetic Disorders of the Indian Subcontinent. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-2231-9_14

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  • DOI: https://doi.org/10.1007/978-1-4020-2231-9_14

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-6262-8

  • Online ISBN: 978-1-4020-2231-9

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