Abstract
Although the term ‘solution’ covers a wide variety of possible combinations of the three states of matter, we shall be concerned in this chapter mainly with homogeneous solutions of solid solutes in liquid solvents (usually aqueous). This type of solution is frequently encountered in pharmacy in such liquid dosage forms as parenteral solutions, eye-drops, infusions and irrigations. Some of the basic thermodynamic properties of solutions will be examined as well as those solution properties such as osmotic pressure, pH, diffusion and viscosity that are of particular interest in pharmacy.
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References
British Pharmaceutical Codex, The Pharmaceutical Press, London, 1973
S. Glasstone. Thermodynamics for Chemists, Van Nostrand, 1947
I.M. Klotz. Chemical Thermodynamics, Benjamin, New York, 1964
A. Cammarata. J. pharm. Sci., 64, 2025 (1975)
K.H. Meyer and H. Hemmi. Biochem. Z. 277, 39 (1935)
J. Ferguson. Proc. r. Soc. B, 127, 387 (1939)
W.H. Streng, H.E. Huber and J.T. Carstensen. J. pharm. Sci., 61, 384 (1978)
The Merck Index, 9th Edition, Merck, 1976
R.A. Robinson and R.H. Stokes. Electrolyte Solutions, Butterworths, 1959
G.L. Flynn, S.H. Yalkowsky and T.J. Roseman. J. pharm. Sci., 63, 479 (1974)
P.J. Dunlop, B.J. Steel and J.E. Lane. Techniques of Chemistry (ed. A. Weissberger), vol. 1, part IV, Wiley-Interscience, 1972, chapter 4
J.W. Mehl, J.L. Oncley and R. Simha. Science, 92, 132 (1940)
G. Schill and K. Gustavii. Acta pharm., suec., 1, 24 (1964)
P.J. Niebergall, R.L. Schnaare and E.T. Sugita. J. pharm. Sci., 61, 232 (1972)
L.J. Leeson, J.E. Krueger and R.A. Nash. Tetrahedron Lett., 18, 1155 (1963)
R.J. Sturgeon and S.G. Schulman. J. pharm. Sci., 66, 958 (1977)
W.H. Streng, H.E. Huber, J.L. De Young and M.A. Zoglio. ibid, 65, 1034 (1976)
W.H. Streng, H.E. Huber, J.L. De Young and M.A. Zoglio. ibid, 66, 1357 (1977)
T. Ishimitsu, S. Hirose and H. Sakurai. Chem. pharm. Bull., 26, 74 (1978)
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© 1981 A.T. Florence and D. Attwood
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Florence, A.T., Attwood, D. (1981). Solutions. In: Physicochemical Principles of Pharmacy. Palgrave, London. https://doi.org/10.1007/978-1-349-19480-3_4
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DOI: https://doi.org/10.1007/978-1-349-19480-3_4
Publisher Name: Palgrave, London
Print ISBN: 978-0-333-44996-7
Online ISBN: 978-1-349-19480-3
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