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Physicochemical Principles of Pharmacy pp 445–493Cite as

Chemical Stability of Drugs

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Abstract

Most drugs are subject to some form of chemical decomposition, particularly when formulated as liquid dosage forms. Some of the consequences of degradation are that the aged medicinal preparation no longer has the desired pharmacological potency. It may also exhibit physical manifestations of decomposition such as the discolouration that often follows photodegradation; or, more seriously (but fortunately, more rarely), it may contain harmful decomposition products.

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Author information

Authors and Affiliations

  1. Department of Pharmaceutics, University of Strathclyde, UK

    A. T. Florence

  2. Department of Pharmacy, University of Manchester, UK

    D. Attwood

Authors
  1. A. T. Florence
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  2. D. Attwood
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© 1981 A.T. Florence and D. Attwood

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Florence, A.T., Attwood, D. (1981). Chemical Stability of Drugs. In: Physicochemical Principles of Pharmacy. Palgrave, London. https://doi.org/10.1007/978-1-349-19480-3_11

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