Abstract
Until the AIDS epidemic, knowledge about cellular immune mechanisms among practising clinicians and health care workers was sketchy; opportunist infections in the immunocompromised host were regarded as recherché and as lists of bizarre organisms to be taken out and dusted down at rare intervals with a sense of the exotic; most lay people had no idea what immunologists were, unless something to do with vaccination; clinicians regarded them as laboratory-based scientists whose language was opaque, whose concepts were rarefied and whose relevance was doubtful; immunologists had uncertainties about the nature of immunosuppression in different contexts and were still grappling with the relevance of immunological tests, both new and old, to clinical diagnosis. AIDS has changed all that.
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Bowen, D. L., Lane, H. C. and Fauci, A. S. (1984). Cellular immunity. In Ebbesen, P., Biggar, R. J. and Melbye, M. (Eds.), AIDS — A Basic Guide for GTinicians, pp. 135–150. Munksgaard, Copenhagen
Cooper, D. A., Gold, J., Maclean, P., Donovan, B., Finlayson, R., Barnes, T. G., Michelmore, H. M., Brooke, P. and Penny, R. (1985). Acute AIDS-retrovirus infection — definition of a clinical illness associated with seroconversion. Lancet, i, 537
Janossy, G., Pinching, A. J., Bofill, M., Weber, J., McLaughlin, J. E., Ornstein, M., Ivory, K., Harris, J. R. W., Favrot, M. and Macdonald-Burns, D. C. (1985). An immunohistological approach to persistent lymphadenopathy and its relevance to AIDS. Clin. Exp. Immunol., 59, 257
Lane, H. C., Masur, H., Edgar, L. C., Whalen, G. and Fauci, A. S. (1983). Abnormalities of B lymphocyte activation and immunoregulation in patients with the acquired immunodeficiency syndrome. New Engl J. Med., 309, 453
Murray, H. W., Rubin, B. Y., Masur, H. and Roberts, R. B. (1984). Impaired production of lymphokines and immune (gamma) interferon in the acquired immunodeficiency syndrome. New EngL J. Med., 310, 883
Pinching, A. J. (1984a). The acquired immune deficiency syndrome. Clin. Exp. Immunol., 56, 1
Pinching, A. J. (1984b). The immunology of AIDS — Meeting report. J. Roy. Soc. Med., 77, 971
Pinching, A. J., McManus, T. J., Jeffries, D. J., Moshtael, O., Donaghy, M., Parkin, J. M., Munday, P. E. and Harris, J. R. W. (1983). Studies of cellular immunity in male homosexuals in London. Lancet, ii, 126
Pinching, A. J. and Weiss, R. A. (1985). AIDS and the spectrum of HTLV-III/LAV infection. Int. Rev. Exp. Pathol., 28 (in press)
Seligmann, M., Chess, L., Fahey, J. L., Fauci, A. S., Lachmann, P. J., L’Age-Stehr, J., Ngu, J., Pinching, A. J., Rosen, P., Spira, T. J. and Wybran, J. (1984). AIDS — An immunologic reevaluation. New Engi J. Med., 311, 1286
Zolla-Pazner, S. (1984). Serology. In Ebbesen, P., Biggar, R. J. and Melbye, M. (Eds.), AIDS — A Basic Guide for Clinicians, pp. 151–172. Munksgaard, Copenhagen
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Pinching, A. (1986). Immunology: Immunological Profile, Pathogenesis and the Role of Diagnostic Tests. In: Miller, D., Weber, J., Green, J. (eds) The Management of AIDS Patients. Palgrave, London. https://doi.org/10.1007/978-1-349-18079-0_2
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DOI: https://doi.org/10.1007/978-1-349-18079-0_2
Publisher Name: Palgrave, London
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