Abstract
Non-steroidal antioestrogens are a group of pharmacological agents that inhibit oestradiolstimulated events both in vivo and in vitro (Sutherland & Jordan, 1981). There is considerable evidence to suggest that the antagonism of oestradiol action is competitive via the oestrogen receptor (Jordan, 1984); however, the precise molecular mechanism of action is unknown.
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References
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Jordan, V.C., Koch, R., Lieberman, M.E., Mittal, S. (1984). Unexpected oestrogenic activity in a derivative of antioestrogenic triphenylethylenes. In: Paton, W., Mitchell, J., Turner, P., Padgham, C., Ashcroft, E. (eds) IUPHAR 9th International Congress of Pharmacology London 1984. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-17615-1_13
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DOI: https://doi.org/10.1007/978-1-349-17615-1_13
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