Abstract
Among the various questions that may be raised in a discussion of pharmacological considerations relative to antiviral agents, we may include: (1) How does one design an effective but non-toxic antiviral agent? (2) Can we deliver the drug to the target site and maintain an antiviral concentration for the required period of time? (Here we are concerned with absorption, distribution, metabolism and excretion of the drug.) (3) How can we avoid or minimize the emergence of a resistant population of virus? (4) How can we prevent the virus from going into the latent state, but once there how can we control its reactivation?
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© 1984 Macmillan Publishers Limited
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Prusoff, W.H., Lin, T.S., Siegel, S.A., Zucker, M.L., Brubaker, W.F., Lee, J.J. (1984). Pharmacological considerations of antiviral agents. In: Paton, W., Mitchell, J., Turner, P. (eds) IUPHAR 9th International Congress of Pharmacology London 1984. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-17613-7_36
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DOI: https://doi.org/10.1007/978-1-349-17613-7_36
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