Abstract
The catecholamine dopamine (3-hydroxytyramine, 4-[2-aminoethyl]-1, 2-benzenediol; 4-[2-aminoethyl]pyrocatechol; α-[3,4-dihydroxyphenyl]-β-aminoethane; 3,4-dihydroxyphenethylamine) is a decarboxylation product of the aromatic amino acid 3,4-dihydroxyphenylanine (DOPA), which is both present in the bloodstream and synthesized from plasma tyrosine within sympathetic neurones and chromaffin cells. In most of these cells, enzymatic machinery exists by which dopamine can be hydroxylated and methylated to form the other catecholamines, noradrenaline and adrenaline (Blaschko, 1959).
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Bell, C. (1984). Dopaminergic nerves. In: Paton, W., Mitchell, J., Turner, P. (eds) IUPHAR 9th International Congress of Pharmacology London 1984. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-17613-7_27
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