Murphy (1978), after suggesting that epidemiology was the recognition and interpretation of nonrandom distribution of characteristics in the population, indicated that substantive genetics was precisely that area of epidemiology which deals with heredity and that it was a fruitful area for development. This reference can be taken as a specific example of the overlap between genetics and epidemiology. There are two rather different aspects of the relevance of genetics to epidemiology: (1) the need to quantify the influence of genetic factors in the aetiology of various diseases; (2), where the role of genetics has been quantified, a wide range of medical-care issues, such as genetic counselling, or determining the suitability of screening techniques to detect abnormality. Wyatt (1982) has recently stressed the need for accurate, complete, and up-to-date information upon which to base estimates of the risk prior to genetic counselling.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Recommended reading
Emery, A. E. H. (1976). Methodology in Medical Genetics: an Introduction to Statistical Methods. Churchill Livingstone, Edinburgh
Emery, A. E. H. (1979). Elements of Medical Genetics. Churchill Livingstone, Edinburgh
Nora, J. J., and Fraser, F. C. (1981). Medical Genetics: Principles and Practice. Lea and Fibiger, Philadelphia
Other references
Albano, W. A., Lynch, H. T., Recabaren, J. A., et al. (1981). Cancer, 47, 2113–8
Alderson, M. R. (1982). Prevention of Cancer, Arnold, London, 33–4
Allen, G. (1965). Prog. med. Genet., 4, 242–69
Allen, G., Harvard, B., and Shields, J. (1967). Acta Genet., 17, 475–81
Altman, D. G. (1982). J. chron. Dis., 35, 411
Barker, D. J. P., and Record, R. G. (1967). Appl. Statist., 16, 13–16
Cederlof, R., Friberg, L., and Lundman, T. (1977). Acta med. Scand. Suppl. 612
Cederlof, R., Rantaslald, I., and Floderus-Myred, J., et al. (1982). Int. J. Epidem., 11, 387–90
Cherry, N., and Kiernan, N. (1976). Br. J. prev. soc. Med., 30, 121–31
Clarke, C. A., Cowan, W. K., Edwards, J. W. et al. (1955). Br. med. J., 2, 643–6
Clarke, C. A., Edwards, J. W., Haddock, R. D., et al. (1956). Br. med. J., 2, 725–31
Colwell, S. (1980). The Family History Book: a Guide to Tracing Your Ancestors. Phaidon, Oxford
Dean, G. (1972). The Porphyrias: a Story of Inheritance and Environment. Pitman, London
Dean, G. (1978). Practitioner, 221, 219–27
Dean, G., and Barnes, H. D. (1959). S. Afr. med. J., 33, 246
Dean, G., and Keane, T. (1972). Br. J. prev. soc. Med., 26, 186–92
Draper, G. J., Heaf, M. M., and Kinnier Wilson, L. M. (1977). J. med. Genet., 14, 81–90
Eaves, L. J., Last, K. A., Young, P. A., and Martin, N. G. (1978). Heredity, 41, 249–320
Ebers, G. C., Paty, D. W., Stiller, C. R., et al. (1982). Lancet, 2, 88–91
Emery, A. E. H. (1976). Methodology in Medical Genetics: an Introduction to Statistical Methods. Churchill Livingstone, Edinburgh
Emery, A. E. H. (1979). Elements of Medical Genetics. Churchill Livingstone, Edinburgh
Eysenck, H. J. (1980). The Causes and Effects of Smoking. Temple Smith, London
Fraser, F. C., Cziezel, A., and Hanson, C. (1982). Lancet, 2, 144–5
Haley, C. S., and Last, K. A. (1981). Hereditary, 247, 221–36
Hauge, M., Harvald, B., Fisher, M., et al. (1968). Acta, genet. med. Gemellol., 17, 315–33
Hook, E. B., and Liss, S. M. (1982). J. chron. Dis., 35, 207–9
Hutchinson, T. P. (1982). J. Epidem. Comm. Hlth, 36, 155–6
Jablon, S., Neel, J. V., Gershowitz, H., and Atkinson, G. F. (1967). Am. J. hum. Genet., 19, 133–61
Kaprio, J., Hammar, N., Koskenvuo, M., et al. (1982). Int. J. Epidem., 11, 378–86
Knox, E. G. (1974). Br. J. prev. soc. Med., 28, 73–80
Lancet (1982). 2, 194–5
Larson, S. L. (1969). Int. Surg., 51, 124–31
Lawler, S. D., and Reeves, B. R. (1976). J. clin. Path., 29, 569–82
Machin, G. A. (1974). Lancet, 1, 549–51
MacMahon, B., and Pugh, T. E. (1970). Epidemiology: Principles and Methods. Little Brown, Boston
Marshall, T., and Knox, E. G. (1980). J. Epidem. Comm. Hlth, 34, 1–8
Melnick, K. (1979). Birth Defects, 15, (3), 19–41
Murphy, E. A. (1978). Int. J. Epidem., 7, 7–14
Peto, J. (1980). In Banbury Report 4: Cancer Incidence in Defined Populations. Cold Spring Harbour Laboratory, Cold Spring Harbour, pp. 203–13
Polani, P. E., and Berry, A. C. (1982). Lancet, 2, 106–7
Schimke, R. N. (1978). Genetics and Cancer in Man. Churchill Livingstone, Edinburgh
Sivak, M. V., Schleutermann, D., Braun, W. A., and Sullivan, B. H. (1981). Cancer, 48, 76–81
Smith, A. (1966). Genetics in Medicine. Livingstone, Edinburgh
Stevenson, S. S., Worcester, J., and Rice, R. G. (1950). Pediatrics, 6, 37–50
Tager, I., Tischler, P. V., Rosner, B., et al. (1978). Int. J. Epidem., 7, 55–62
Waterhouse, J. A. H. (1950). Br. J. Soc. Med., 4, 197–216
Weatherall, J. A. C. (1982). Hlth Trends, 14, 85–8
World Health Organisation (1966). W.H.O. Chron., 20, 121
Wyatt, P. R. (1982). Lancet, 2, 1051
Author information
Authors and Affiliations
Copyright information
© 1983 Michael Alderson
About this chapter
Cite this chapter
Alderson, M. (1983). Genetic Studies. In: An Introduction to Epidemiology. Palgrave, London. https://doi.org/10.1007/978-1-349-17291-7_9
Download citation
DOI: https://doi.org/10.1007/978-1-349-17291-7_9
Publisher Name: Palgrave, London
Print ISBN: 978-0-333-35015-7
Online ISBN: 978-1-349-17291-7
eBook Packages: MedicineMedicine (R0)