Abstract
Most drugs are subject to some form of chemical decomposition, particularly when formulated as liquid dosage forms. Some of the consequences of degradation are that the aged medicinal preparation no longer has the desired pharmacological potency. It may also exhibit physical manifestations of decomposition such as the discolouration that often follows photodegradation; or, more seriously (but fortunately, more rarely), it may contain harmful decomposition products.
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© 1988 A. T. Florence and D. Attwood
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Florence, A.T., Attwood, D. (1988). Chemical Stability of Drugs. In: Physicochemical Principles of Pharmacy. Palgrave, London. https://doi.org/10.1007/978-1-349-16558-2_4
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