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Properties of the Solid State

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Physicochemical Principles of Pharmacy

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Abstract

The physical properties of the solid state of both drugs and adjuvants are of considerable interest as they can affect both the production of dosage forms and the biological behaviour of the finished form. Powders, as Pilpell reminds us, ‘can float like a gas, flow like a solid or support a weight in the same way as hard-packed snow’. We deal with aerosolised powders in chapter 9, and some properties of compacted solids in chapter 6, but here our main interest is in the effect of crystallinity and particle size on drug behaviour especially dissolution and bioavailability.

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Author information

Authors and Affiliations

  1. Department of Pharmacy, University of Strathclyde, UK

    A. T. Florence

  2. Department of Pharmacy, University of Manchester, UK

    D. Attwood

Authors
  1. A. T. Florence
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  2. D. Attwood
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© 1988 A. T. Florence and D. Attwood

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Florence, A.T., Attwood, D. (1988). Properties of the Solid State. In: Physicochemical Principles of Pharmacy. Palgrave, London. https://doi.org/10.1007/978-1-349-16558-2_2

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  • DOI: https://doi.org/10.1007/978-1-349-16558-2_2

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-0-333-23405-1

  • Online ISBN: 978-1-349-16558-2

  • eBook Packages: MedicineMedicine (R0)

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