Reproductive Failure and Wastage

  • D. J. Begley
  • J. A. Firth
  • J. R. S. Hoult
Chapter

Abstract

We are all well aware of imperfections and wastage in the human reproductive process such as the pregnancy which ends in a miscarriage or a stillbirth and that tragically embodied in the child who suffers a major deformity or permanent handicap. These distressing outcomes of pregnancy are reminders that human reproduction is fallible and that conception does not automatically result in the birth of a live and healthy infant. The causes of failure and the inefficiencies of the human reproductive process are discussed in this chapter, with special emphasis on those developmental errors which give rise to abnormalities of the newborn.

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Further reading

  1. Catalano, L. W. and Sever, J. L. (1971). ‘The role of viruses as causes of congenital defects’, Annual Review of Microbiology, 25, 255CrossRefGoogle Scholar
  2. Emery, A. E. H. (ed.) (1973). Antenatal Diagnosis of Genetic Disease, Churchill Livingstone, LondonGoogle Scholar
  3. Harris, H. (1975). The Principles of Human Biochemical Genetics, North-Holland, AmsterdamGoogle Scholar
  4. Mirkin, B. L. (ed.) (1976). Perinatal Pharmacology and Therapeutics, Academic Press, LondonGoogle Scholar
  5. Raivio, K. O. and Seegmiller, J. E. (1972). ‘Genetic diseases of metabolism’, Annual Review of Biochemistry, 41, 543CrossRefGoogle Scholar
  6. Scrimgeour, J. B. (ed.) (1978). Towards the Prevention of Fetal Malformation, Edinburgh University PressGoogle Scholar
  7. Wilson, J. G. (1977). ‘Teratogenic effects of environmental chemicals’, Federation Proceedings, 36, 1698Google Scholar
  8. Berry, C. L. (ed.) (1976). ‘Human malformation’, British Medical Bulletin, 32(1), 1–89Google Scholar

Copyright information

© D. J. Begley, J. A. Firth and J. R. S. Hoult 1980

Authors and Affiliations

  • D. J. Begley
    • 1
  • J. A. Firth
    • 2
  • J. R. S. Hoult
    • 1
  1. 1.King’s CollegeLondonUK
  2. 2.St George’s Hospital Medical SchoolLondonUK

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