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Aspects of Midwifery Practice pp 109–131Cite as

HIV and pregnancy

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Part of the book series: Midwifery Practice Series

Abstract

The epidemic of infection with Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) to which it leads has had enormous impact on women and babies worldwide. The World Health Organisation (WHO) estimates that in the 13 years since the transmission of Human Immunodeficiency Virus Type 1 (HIV-1) from a mother to her child was first reported (Rogers et al 1987), there have been about 500 000 cases of AIDS in women and children worldwide, most of which have been unrecognised (Chin 1990). By early 1990, the WHO estimated that more than three million women, most of child bearing age, were infected with HIV, about 80 per cent of whom were in sub-Saharan Africa. It has been suggested that during the 1990s an additional three million women and children world wide will die as a consequence of the epidemic (Chin 1990).

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References

  • Ades AE, Davison CF, Holland FJ, Gibb DM, Hudson CN, Nichols A, Goldberg D, Peckham CS 1993 Vertically transmitted HIV infection in the British Isles. British Medical Journal 306: 1296–9

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Bardequez A, Johnson MA 1994 Women and HIV-1 infection. AIDS 8 (suppl 1): S261–73

    Google Scholar 

  • Berer M 1993 Women and HIV/AIDS. An international resource book. Pandora, London

    Google Scholar 

  • Brierley J 1993 HIV and AIDS in childbirth: are midwives responding to the needs of women? Midwives Chronicle 106 (1268): 317–25

    CAS  PubMed  Google Scholar 

  • Blanche S, Mayaux MJ, Rouzioux C et al 1994 Relation of the course of HIV infection in children to the severity of the disease to their mothers at delivery. New England Journal of Medicine 330: 308–12

    Article  CAS  PubMed  Google Scholar 

  • Chin J 1990 Current and future dimensions of the HIV/AIDS pandemic in women and children. Lancet 336: 221–4

    Article  CAS  PubMed  Google Scholar 

  • Concorde Coordinating Committee 1994 Concorde: MRC/ANRS randomised double-blind controlled trial of immediate and deferred zydovudine in symptom-free HIV infection. Lancet 343: 871–81

    Article  Google Scholar 

  • Department of Health 1994 Guidelines for offering voluntary named HIV antibody testing to women receiving antenatal care. HMSO, London

    Google Scholar 

  • Deschamps MM, Pape JW, Desvarieux M et al 1993 A prospective study of HIV-seropositive asymptomatic women of childbearing age in a developing country. Journal of Acquired Immune Deficiency Syndromes 6 (5): 446–51

    Article  CAS  PubMed  Google Scholar 

  • Dunn DT, Newell ML, Ades AE, Peckham CS 1992 Risk of human immunodeficiency virus type 1 transmission through breastfeeding. Lancet 340: 585–8

    Article  CAS  PubMed  Google Scholar 

  • Ehrnst A, Lindgren S, Dictor M et al 1991 HIV in pregnant women & their offspring: evidence for late transmission. Lancet 338: 203–7

    Article  CAS  PubMed  Google Scholar 

  • European Collaborative Study 1991 Children born to women with HIV-1 infection: natural history and risk of transmission. Lancet 337: 253–60

    Article  Google Scholar 

  • European Collaborative Study 1992 Risk factors for mother-to-child transmission of HIV-1. Lancet 339: 1007–12

    Article  Google Scholar 

  • European Collaborative Study 1994 Caesarean section and the risk of vertical transmission of HIV-1 infection. Lancet 343: 1464–7

    Article  Google Scholar 

  • Expert Maternity Group 1993 Changing childbirth. HMSO, London

    Google Scholar 

  • Gibb D, Wara D 1994 Paediatric HIV infection. AIDS 8 (suppl 1): S275–83

    Google Scholar 

  • Global Program on AIDS 1992 Current and future dimensions of the HIV/AIDS pandemic: a capsule summary. WHO, Geneva

    Google Scholar 

  • Goedert JJ, Mendez H, Drummond JE et al 1989 Mother-to-infant transmission of human immunodeficiency virus type 1: association with prematurity or low anti-gp 120. Lancet ii: 1351–4

    Google Scholar 

  • Goedert JJ, Duliege AM, Amos CI et al 1991 High risk of HIV-1 infection for first born twins. Lancet 338: 1471–5

    Article  CAS  PubMed  Google Scholar 

  • Hankins CA 1990 Issues involving women, children and AIDS primarily in the developed world. Journal of Acquired Immune Deficiency Syndromes 3: 443–8

    CAS  PubMed  Google Scholar 

  • House of Commons Health Committee 1992 Second report: Maternity Services Vol. 1. HMSO, London

    Google Scholar 

  • Johnstone FD, MacCallum L, Brettle R et al 1988 Does infection with HIV affect the outcome of pregnancy? British Medical Journal 296: 467

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Johnstone FD, Willox L, Brettle RP 1992 Survival time after AIDS in pregnancy. British Journal of Obstetrics and Gynaecology 99: 633–6

    Article  CAS  PubMed  Google Scholar 

  • Jovaisas E, Koch MA, Schafer A 1986 LAV/HTLV-III in a 20 week fetus (letter). Lancet ii: 1129

    Google Scholar 

  • Kesson A, Sorrell T 1993 Human immunodeficiency virus infection in pregnancy. Baillière’s Clinics in Obstetrics & Gynaecology 7 (1): 45–74

    Article  CAS  Google Scholar 

  • Krivine A, Ghislaine F, Linsen C et al 1992 HIV replication during the first weeks of life. Lancet 339: 1187–9

    Article  CAS  PubMed  Google Scholar 

  • Lancet Editorial 1994 Zidovudine for mother, fetus, and child: hope or poison? Lancet 334 (8917): 207–9

    Google Scholar 

  • Lewis SH, Reynolds-Kohler C, Fox HE et al 1990 HIV-1 in trophoblastic and villous Hofbauer cells and haemotological precursors in eight-week fetuses. Lancet 335: 565–8

    Article  CAS  PubMed  Google Scholar 

  • Lipsky JJ 1994 Commentary: Concorde lands. Lancet 343: 866–7

    Article  CAS  PubMed  Google Scholar 

  • MacCallum LR, France AJ, Jones ME, Steel CM, Burns SM, Brettle RP et al 1988 The effects of pregnancy on the progression of HIV infection. IV International Conference an AIDS. Stockholm, June 1988; abstract 4032

    Google Scholar 

  • Minkoff HL, De Hovitz JA 1990 Care of women infected with the human immunodeficiency virus. Journal of the American Medical Association 261 (9): 1289–94

    Google Scholar 

  • Minkoff HL, Willoughby A, Mendez H et al 1990 Serious infections during pregnancy among women with advanced immunodeficiency virus infection. American Journal of Obstetrics and Gynecology 162 (1): 30–4

    Article  CAS  PubMed  Google Scholar 

  • Morbidity and Mortality Weekly Report 1994 Zidovudine for the prevention of HIV transmission from mother to infant. Morbidity and Mortality Weekly Report 43: 285–7

    Google Scholar 

  • Nair P, Alger L, Hines S et al 1993 Maternal and neonatal characteristics associated with HIV infection in infants of seropositive women. Journal of Acquired Immune Deficiency Syndromes 6: 298–302

    CAS  PubMed  Google Scholar 

  • Newell ML, Peckham C 1993 Risk factors for vertical transmission of HIV-1 and early markers of HN-1 infection in children. AIDS 7: S591–7

    Article  Google Scholar 

  • Newell ML, Peckham C 1994 Working towards a European strategy for intervention to reduce vertical transmission of HIV. British Journal of Obstetrics and Gynaecology 101: 192–6

    Article  CAS  PubMed  Google Scholar 

  • O’Sullivan MJ, Boyer PJJ, Scott GB et al 1993 The pharmokinetics and safety of zidovudine in the third trimester of pregnancy for women infected with human imunodeficiency virus and their infants: Phase I Acquired Immunodeficiency Syndrome Clinical Trials Group study (protocol 082). American Journal of Obstetrics and Gynecology 168: 1510–16

    Article  PubMed  Google Scholar 

  • Pratt R 1991 AIDS: a strategy for nursing care 3rd edn. Edward Arnold, London

    Google Scholar 

  • Public Health Laboratory Service 1993 Unlinked anonymous monitoring of HN prevalence in England and Wales: 1990–92. Communicable Disease Report Review 3 (1): 8

    Google Scholar 

  • Rogers MF, Thomas PF, Starcher ET et al 1987 Acquired immunodeficiency syndrome in children: Reports of the Centers for Disease Control national surveillance, 1982–1985. Pediatrics 79: 1008–14

    CAS  PubMed  Google Scholar 

  • Rogers MF, Chin-Yih O, Rayfield M et al 1989 Use of the polymerase chain reaction for early detection of the proviral sequences of human immunodeficiency virus in infants born to seropositive mothers. New England Journal of Medicine 320: 1649–54

    Article  CAS  PubMed  Google Scholar 

  • Roth C, Brierley J 1990 HN infection — a midwifery perspective. In Alexander J, Levy V, Roch S (eds) Intrapartum care: a research-based approach (Midwifery Practice Vol 2 ). Macmillan, Basingstoke

    Google Scholar 

  • Royal College of Obstetricians and Gynaecologists 1994 National study of HIV in pregnancy. Newsletter 20, September 1994. RCOG, London

    Google Scholar 

  • Ryder RW, Hassig S 1988 The epidemiology of perinatal transmission of HIV. AIDS 2 (suppl 1): S83–9

    Article  PubMed  Google Scholar 

  • Ryder RW, Nsa W, Behets F, Vercauteren G, Baende E et al 1988 Perinatal transmission in two African hospitals: one year follow-up. IV International Conference on AIDS, Stockholm, June 1988, abstract 4128

    Google Scholar 

  • Ryder RW, Nsa W, Hassig S et al 1989 Perinatal transmission of the human immunodeficiency virus type 1 to infants of seropositive women in Zaire. New England Journal of Medicine 320: 1637–42

    Article  CAS  PubMed  Google Scholar 

  • Schaefer A, Grosch-Woener I, Friedmann W, Kunze R, Mielke M, Jiminez E 1988 The effects of pregnancy on the natural course of the HIV infection. IV International Conference on AIDS, Stockholm, June 1988, abstract 4039

    Google Scholar 

  • Scharf E 1992 Research: HIV, AIDS and the invisibility of women. In O’Sullivan S, Thomson K (eds) Positively women. Sheba, London

    Google Scholar 

  • Schoenbaum EE, Davenny K, Selwyn PA 1988 The impact of pregnancy on HIV-related disease. In Hudson C, Sharp F (eds) AIDS and obstetrics and gynaecology. Proceedings of the 19th Royal College of Obstetricians and Gynaecologists Study Group. RCOG, London

    Google Scholar 

  • Selwyn PA, Schoenbaum EE, Davenny K, Robertson VJ, Feingold AF et al 1989 Prospective study of human immunodeficiency virus infection and pregnancy outcomes in intravenous drug users. Journal of the American Medical Association 261 (9): 1289–94

    Article  CAS  PubMed  Google Scholar 

  • Sperling RS, Stratton P, O’Sullivan MJ et al 1992 A survey of zidovudine use in pregnant women with human immunodeficiency virus infection. New England Journal of Medicine 326: 857–61

    Article  CAS  PubMed  Google Scholar 

  • Sprecher S, Soumenkoff G, Puissant F et al 1986 Vertical transmission of HIV in 15-week fetus. Lancet 2: 288–9

    Article  CAS  PubMed  Google Scholar 

  • Thiry L, Sprecher-Goldberger S, Jockheer T et al 1985 Isolation of AIDS virus from cell free breast milk of three healthy virus carriers. Lancet ii: 891–2

    Google Scholar 

  • Van de Perre P, Simonon A, Hitimana D et al 1993 Infective and anti-infective properties in breastmilk from HIV-I-infected women. Lancet 341: 914–18

    Article  PubMed  Google Scholar 

  • Vogt MV, Witt DJ, Craven DE et al 1986 Isolation of HTLVIII/LAV from cervical secretions of women at risk for AIDS. Lancet 1: 525–7

    Article  CAS  PubMed  Google Scholar 

  • Weiblen BJ, Lee FK, Cooper ER et al 1990 Early diagnosis of HIV infection in infants by detection of IgA HIV antibodies. Lancet 335: 988–90

    Article  CAS  PubMed  Google Scholar 

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Authors
  1. Carolyn Roth
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Editor information

Jo Alexander Valerie Levy Sarah Roch

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© 1995 Carolyn Roth

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Roth, C. (1995). HIV and pregnancy. In: Alexander, J., Levy, V., Roch, S. (eds) Aspects of Midwifery Practice. Midwifery Practice Series. Palgrave, London. https://doi.org/10.1007/978-1-349-13543-1_6

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  • DOI: https://doi.org/10.1007/978-1-349-13543-1_6

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-0-333-61956-8

  • Online ISBN: 978-1-349-13543-1

  • eBook Packages: MedicineMedicine (R0)

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