Galanin pp 321-329 | Cite as

Role of galanin in prolactin and growth hormone secretion in rats

  • A. Shimatsu
  • T. Tanoh
  • H. Koshiyama
  • Y. Murakami
  • Y. Kato
  • N. Yanaihara
  • H. Imura
Chapter
Part of the Wenner-Gren Center International Symposium Series book series

Abstract

Galanin (GAL), a 29 amino acid peptide, was first isolated from porcine intestine (Tatemoto et al.,1983). GAL is widely distributed in the rat brain (Rokaeus et al.,1984; Ch’ng et al.,1985 ; Skofitsch and Jacobowitz,1985; Melander et al.,1986a). In the central nervous system (CNS), the hypothalamus is rich in fibers and cell bodies containing GAL. Specific binding sites for the peptide were found in the hypothalamus, including the median eminence of the rat (Nordström et al.,1986; Melander et al., 1986b). These observations suggest that GAL is involved in regulating anterior pituitary function as a neurotransmitter or a neuromodulator in the CNS.

Keywords

Serotonin Propranolol Prolactin Clonidine Naloxone 

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Copyright information

© The Wenner-Gren Center 1991

Authors and Affiliations

  • A. Shimatsu
  • T. Tanoh
  • H. Koshiyama
  • Y. Murakami
  • Y. Kato
  • N. Yanaihara
  • H. Imura

There are no affiliations available

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