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Development of antioxidant defences in preterm infants

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The Surfactant System of the Lung
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Abstract

Bronchopulmonary dysplasia is one of the most common sequelae of neonatal intensive care, and the problems of its prevention and treatment are still largely unsolved. The mechanism of development of this disease remains a vexing question, even though it has been unanimously accepted for many years that oxygen toxicity plays a role [1]. Investigation of tissue injury caused by oxygen has clearly demonstrated that the damage arises from a complex process in which the production of toxic molecular species of oxygen is not balanced by the activity of the antioxidant system [2].

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© 1991 Macmillan Publishers Limited

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Bracci, R., Buonocore, C., Berni, S., De Nisi, G., Gioia, D. (1991). Development of antioxidant defences in preterm infants. In: Cosmi, E.V., Di Renzo, G.C., Anceschi, M.M. (eds) The Surfactant System of the Lung. Palgrave, London. https://doi.org/10.1007/978-1-349-12553-1_27

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  • DOI: https://doi.org/10.1007/978-1-349-12553-1_27

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-1-349-12555-5

  • Online ISBN: 978-1-349-12553-1

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