Abstract
We are all familiar with the term benzodiazepine, as are a significant proportion of the general public. In the public domain it is a term synonymous with diazepam that connotes dependence and withdrawal. The scientific community also has its misconceptions about the term benzodiazepine, which is perhaps not surprising given the speed of evolution of our knowledge about these drugs, their receptors and the uniqueness of their pharmacology. In no other field of CNS pharmacology has such a short time elapsed between the discovery of a receptor and its cloning and expression. It is at times hard to believe that the first report of brain-specific benzodiazepine receptors was made only 12 years ago (Squires and Braestrup, 1977; Mohler and Okada, 1978). Not surprisingly, some of the more recent and novel aspects of benzodiazepine pharmacology have not yet been fully assimilated.
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Nutt, D. (1990). Selective Ligands for Benzodiazepine Receptors: Recent Developments. In: Osborne, N.N. (eds) Current Aspects of the Neurosciences. Palgrave, London. https://doi.org/10.1007/978-1-349-11922-6_9
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