Abstract
Our current model for describing the terminal stages of murine leukemia virus (MLV) morphogenesis is presented in Figure 1. It is derived from biochemical and ultrastructural results of ours and other laboratories, over the past 15–20 years (Luftig and Kilham, 1971; Bolognesi, Luftig and Shaper, 1973; Yoshinaka and Luftig, 1977a,b; Jamjoom, Naso and Arlinghaus, 1976; Yoshinaka et al., 1985; Katoh et al., 1985; Traktman and Baltimore, 1982; Crawford and Goff, 1985; Ikuta and Luftig, 1988). A critical role is noted for polyproteins Pr6gag and Pr180gag-Pol, as well as the viral encoded protease (PR) in the final stages of assembly.
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References
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© 1990 Macmillan Publishers Limited
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Luftig, R., Ikuta, K., Bu, M., Calkins, P. (1990). Terminal Stages of Retrovirus Morphogenesis. In: Pearl, L.H. (eds) Retroviral Proteases. Palgrave, London. https://doi.org/10.1007/978-1-349-11907-3_15
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DOI: https://doi.org/10.1007/978-1-349-11907-3_15
Publisher Name: Palgrave, London
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