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An Introduction to the Blood-Brain Barrier pp 195–272Cite as

Peptides and Proteins

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Abstract

Peptides are short chains of amino acids containing, usually, less than 50–100 residues linked by peptide bonds. A number of peptides have been shown to exist in the cell bodies, as well as in the axons and nerve terminals, of the central nervous system and, by definition, these are called brain peptides or neuropeptides. Neuropeptides have been identified in different brain regions, and neuronal peptidergic pathways have been visualized and characterized in the central nervous system by means of different immunocytochemical, immunofluorescence and radioreceptor assay techniques. For most brain peptides, the localization of their neuronal pathways has been one of the most powerful tools in the understanding of their functions.

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Authors and Affiliations

  1. Sherrington School of Physiology UMDS, Guy’s and St Thomas’s Hospitals, London, UK

    Hugh Davson (Emeritus Professor) & Malcolm B. Segal (Reader in Physiology)

  2. USC School of Medicine, Los Angeles, USA

    Berislav Zloković (Associate Professor of Neurosurgery, Physiology and Biophysics)

  3. School of Medicine, Belgrade, Serbia

    Ljubisa Rakić (Professor of Neurobiology and Biochemistry)

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  1. Hugh Davson
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  2. Berislav Zloković
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  3. Ljubisa Rakić
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  4. Malcolm B. Segal
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Davson, H., Zloković, B., Rakić, L., Segal, M.B. (1993). Peptides and Proteins. In: An Introduction to the Blood-Brain Barrier. Palgrave, London. https://doi.org/10.1007/978-1-349-11882-3_3

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  • DOI: https://doi.org/10.1007/978-1-349-11882-3_3

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