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New Concepts in Anxiety pp 440–457Cite as

Bidirectional Activity of Benzodiazepine-receptor Ligands in Cognitive Functions in Humans

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Abstract

Over the past three decades benzodiazepines (BDZ) have become a popular class of drugs for the treatment of various physical and emotional disorders. Their most prevalent use is as antianxiety agents, but they are also used as muscle relaxants and anticonvulsants, and in the treatment of sleep disorders. Their main appeal is the reported absence of severe side effects during their use. However, initial administration of BDZ in therapeutic doses induces a wide array of cognitive impairments.

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Author information

Authors and Affiliations

  1. Human Pharmacology Unit II, Schering AG, Postfach 65 03 11, D-1000, Berlin 65, West Germany

    T. Duka

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  1. T. Duka
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Editor information

Editors and Affiliations

  1. Pierre Fabre Médicament, Castres, France

    M. Briley

  2. Psychopharmacology Research Unit, UMDS, Guy’s Hospital, London, SE1 9RT, UK

    S. E. File

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© 1991 Macmillan Publishers Limited

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Duka, T. (1991). Bidirectional Activity of Benzodiazepine-receptor Ligands in Cognitive Functions in Humans. In: Briley, M., File, S.E. (eds) New Concepts in Anxiety. Palgrave, London. https://doi.org/10.1007/978-1-349-11847-2_35

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  • DOI: https://doi.org/10.1007/978-1-349-11847-2_35

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-1-349-11849-6

  • Online ISBN: 978-1-349-11847-2

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