Introduction and Methods
During the past forty years, the number of deaths attributable to colorectal cancer in the United Kingdom, has remained depressingly constant at around 20,000 per annum (Cancer Research Campaign 1989). However, during this time substantial advances have been made in our understanding of the biological behaviour of this capricious disease. Not least among these is the fact that at the time of its clinical presentation many, if not the majority, of the patients thus afflicted are already beyond the stage when surgical treatment alone can hope to effect a cure. This present study re-affirms, yet again, that curative resection of the tumour is only feasible in about 50% of these patients.
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