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Production and assessment of antibodies

  • Chapter
Principles and Practice of Immunoassay

Abstract

A suitable antibody is the common feature of all immunoassay systems, whether they be of the limited or excess reagent type, and whatever the form of label used for quantitation since the technique was introduced by Yalow & Berson in 1960 (1). Immunoassay use both precipitating and non-precipitating antibodies in the primary antigen:antibody reaction and these can be distinguished irrrespective of whether the primary antibody is in the free state or is covalently coupled or adsorbed to a solid phase.

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Authors
  1. Jacky Burrin
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  2. David Newman
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Editor information

Editors and Affiliations

  1. Department of Clinical Biochemistry, London Hospital Medical College, Turner Street, E1 2AD, London, UK

    Christopher P. Price (Professor and Director) & David J. Newman (Principal Research Scientist) (Professor and Director) &  (Principal Research Scientist)

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© 1991 Palgrave Macmillan, a division of Macmillan Publishers Limited

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Burrin, J., Newman, D. (1991). Production and assessment of antibodies. In: Price, C.P., Newman, D.J. (eds) Principles and Practice of Immunoassay. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-11234-0_2

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