Abstract
In more than three per cent of births the baby has a serious structural malformation, genetic disorder or chromosome abnormality which is going to interfere with survival or the quality of life. Some of these abnormalities, such as anencephaly or many of the gross malformation syndromes, are lethal and inoperable. Others, such as haemophilia and phenylketonuria are treatable and some, such as cleft lip and palate and gastroschisis, are correctable. Many of these abnormalities can now be accurately diagnosed before 28 weeks gestation and mostly during the fourth month of pregnancy, early enough within the present law for selective abortion to be considered by the parents (Laurence, 1980).
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References
Brewer, C. (1978) ‘Induced abortion after feeling foetal movements; its causes and emotional consequences’, Journal of Biosocial Science, vol. 10, pp. 203–8.
Donnai, P., N. Charles and R. Harris (1981) ‘Attitudes of patients after “genetic” termination of pregnancy’, British Medical Journal, vol. 282, pp. 621–2.
Elder, S. and K. M. Laurence (1991) ‘The impact of supportive intervention after second trimester termination of pregnancy for fetal malformation’. Prenatal Diagnosis vol. 11 (in press).
Emery, A. E. H. (1973) Antenatal Diagnosis of Genetic Disease ( Edinburgh: Churchill Livingstone).
Forrest, G. C., E. Standish and J. D. Baum (1982) ‘Support after perinatal death: a study of support and counselling after perinatal bereavement’, British Medical Journal, vol. 285, pp. 1475–9.
Handy, J. A. (1982) ‘Psychological and social aspects of induced abortion’, British Journal of Psychology, vol. 21, pp. 29–49.
Harris, B. (1989) personal communication.
Laurence, K. M. (1980) ‘Prenatal diagnosis, selective abortion and the Abortion (Amendment) Bill’, Lancet, no. i; pp. 249–50.
Laurence, K. M. (1985) ‘Prevalence of neural tube defect in two counties in South Wales over three decades illustrating the need for continued action and vigilance’, Zeitschrift fur Kinderchirugie, vol. 40, suppl. 1, pp. 58–60.
Laurence, K. M. (1989) ‘A declining incidence of neural tube defects in the U.K’., Zeitschrift fur Kinderchirugie, vol. 44, suppl. 1, p. 51.
Lloyd, J. and K. M. Laurence (1985) ‘Sequelae and support after termination of pregnancy for fetal malformation’, British Medical Journal, vol. 290, pp. 907–9.
Roberts, C. J., K. T. Evans, B. M. Hibbard, K. M. Laurence, E. E. Roberts and I. B. Robertson (1983) ‘Diagnostic effectiveness of ultrasound in the detection of neural tube defect: South Wales experience of 2509 high risk scans (1977–1982)’, Lancet, no. ii, pp. 1088–9.
Roberts, C. J., B. M. Hibbard, G. H. Elder, K. T. Evans, K. M. Laurence, A. Roberts, J. S. Woodhead, I. B. Robertson and M. Hoole (1983) ‘Efficacy of a serum AFP screening service for neural tube defect: the South Wales experience’, Lancet, no. i, pp. 1315–8.
UK Collaborative study (1977) ‘Measurement of maternal serum alphafeto protein as a screening test for the antenatal diagnosis of anencephaly and spina bifida in early pregnancy’, Lancet, no. i, pp. 1323–32.
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© 1991 The Galton Institute
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Laurence, K.M. (1991). Fetal Diagnosis and the Need for Support. In: Roberts, D.F., Chester, R. (eds) Molecular Genetics in Medicine. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-10874-9_6
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DOI: https://doi.org/10.1007/978-1-349-10874-9_6
Publisher Name: Palgrave Macmillan, London
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