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The Assessment of Pharmacokinetics

  • Chapter
Early Phase Drug Evaluation in Man

Abstract

Pharmacokinetic assessment of new drug entities forms a pivotal part of any pharmaceutical development programme. Although primarily providing data to support toxicological and efficacy studies, carefully designed and executed pharmacokinetic studies in early drug development can greatly enhance decision-making processes involved in formulation development, as well as providing indications of potential problems that may arise later in the clinical assessment of the new drug entity.

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Author information

Authors and Affiliations

  1. Medeval Ltd, University of Manchester, Manchester, M15 4SH, UK

    Stephen Toon

Authors
  1. Stephen Toon
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Editor information

Editors and Affiliations

  1. May and Baker Pharmaceuticals Rhône-Poulenc Ltd, Dagenham, RM10 7XS, UK

    John O’Grady MD, FRCP (Medical Director, Visiting Professor of Clinical Pharmacology) (Medical Director, Visiting Professor of Clinical Pharmacology)

  2. University of Vienna, Austria

    John O’Grady MD, FRCP (Medical Director, Visiting Professor of Clinical Pharmacology) (Medical Director, Visiting Professor of Clinical Pharmacology)

  3. Clinical Development Unit 1, The Upjohn Company, Kalamazoo, MI, 49001, USA

    Otto I. Linet MD, PhD (Director) (Director)

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© 1990 The editors and contributors

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Toon, S. (1990). The Assessment of Pharmacokinetics. In: O’Grady, J., Linet, O.I. (eds) Early Phase Drug Evaluation in Man. Palgrave, London. https://doi.org/10.1007/978-1-349-10705-6_19

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  • DOI: https://doi.org/10.1007/978-1-349-10705-6_19

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-1-349-10707-0

  • Online ISBN: 978-1-349-10705-6

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