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Different Recognition Sites for Serotonin: The Neuronal Na+-dependent Transporter and the Release-modulating Autoreceptor

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Serotonin

Abstract

A number of pharmacologically distinct recognition sites for serotonin (5-hydroxytryptamine; 5-HT) have been identified at serotoninergic synapses of the CNS. Post-synaptically, these 5-HT binding sites have been associated with 5-HT1-like, 5-HT2 and 5-HT3 receptors. In this short overview, however, attention will be restricted to pre-synaptic recognition sites for 5-HT which are involved in the release and neuronal uptake of 5-HT.

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Langer, S.Z., Graham, D. (1989). Different Recognition Sites for Serotonin: The Neuronal Na+-dependent Transporter and the Release-modulating Autoreceptor. In: Mylecharane, E.J., Angus, J.A., de la Lande, I.S., Humphrey, P.P.A. (eds) Serotonin. Satellite Symposia of the IUPHAR 10th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-10114-6_30

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