Abstract
Many open questions persist concerning the precise role of serotoninergic mechanisms in behavioural control. One of the major reasons for incomplete understanding has been the use of pharmacological tools devoid of selectivity for the three populations of 5-HT receptors described so far, namely 5-HT1-like, 5-HT2 and 5-HT3, and the various subtypes of 5-HT1binding sites thought to exist in the CNS. With the availability of novel drugs showing appreciable degrees of affinity and selectivity for these sites, it is now possible to re-examine the functional roles of 5-hydroxytryptamine (5-HT). A general survey of the behavioural actions of 5-HT has been provided by Mark Tricklebank; detailed data on specific aspects were presented by Michael Tyers and by Paul Bevan, and their colleagues. The following paradigms are of interest in relation to several 5-HT receptor subtypes.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Copyright information
© 1989 The editors and contributors
About this chapter
Cite this chapter
Langer, S.Z. (1989). Behavioural Actions of 5-Hydroxytryptamine: An Overview. In: Mylecharane, E.J., Angus, J.A., de la Lande, I.S., Humphrey, P.P.A. (eds) Serotonin. Satellite Symposia of the IUPHAR 10th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-10114-6_14
Download citation
DOI: https://doi.org/10.1007/978-1-349-10114-6_14
Publisher Name: Palgrave Macmillan, London
Print ISBN: 978-1-349-10116-0
Online ISBN: 978-1-349-10114-6
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)