Abstract
The main purpose of this chapter is to summarize the importance of changes in the composition, structure and properties of the extracellular matrix of connective tissues. These changes may occur during normal development and ageing or as a consequence of pathology. Such biological changes invariably involve degradation of the matrix and/or the synthesis of new components by the cells. However, as explained below, it is not straightforward to define the differences between ageing and degeneration or between degeneration and pathology. Furthermore, even if the distinction were clear, it would often be difficult to separate the effects in practice, since degeneration and pathology of connective tissues are frequently associated with ageing.
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Hukins, D.W.L. (1990). Dynamic Aspects of Connective Tissue Structure and Function. In: Hukins, D.W.L. (eds) Connective Tissue Matrix. Topics in Molecular and Structural Biology. Palgrave, London. https://doi.org/10.1007/978-1-349-09865-1_1
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DOI: https://doi.org/10.1007/978-1-349-09865-1_1
Publisher Name: Palgrave, London
Print ISBN: 978-1-349-09867-5
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