Abstract
Most new drug development takes place in developed countries. Naturally, much of the research takes place in the ‘Western World’, from the discovery of an original compound, or improved variant of an old one, through the laboratory and animal and human clinical pharmacology. However, in recent years Japan has made major contributions, particularly in the area of new compound synthesis.
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Looareesuwan S, White N J, Warreil D A, et al. Studies of mefloquine bioavailability and kinetics using a stable isotope technique: a comparison of the Thai patients with falciparum malaria and healthy Caucasian volunteers. Br J Clin Pharmacol 1987 (in press).
Probst P J, Schwartz D E, Kleinbloesem C H. Ethnic differences in the disposition of the anti-malarial mefloquine (Larium R) following a single oral dose. In: Abstracts of the IXth international congress of infectious and parasitic diseases, Munich, July 20–6, 1986. Munich: Futuramed Verlag, 1986; No. 237.
Cook I F, Cochrane J P, Edstein M D. Race-linked differences in serum concentrations of dapsone monoacetyldapsone and pyrimethamine during malaria prophylaxis. Trans R Soc Trop Med Hyg 1986;80:897–901.
Zhou H H, Chan Y P M, Arnold K, et al. Single-dose pharmacokinetics of ceftriaxone in healthy Chinese adults. J Antimicrob Chemother 1985;27:192–6.
Lasagna L. On reducing waste in foreign clinical trials and postregulation experience. Clin Pharmacol Ther 1986;40:369–72.
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© 1988 The International Federation of Associations of Pharmaceutical Physicians
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Arnold, K. (1988). Developing countries and their rôle in new drug development: a south-east Asian perspective. In: Burley, D., Haward, C., Mullinger, B. (eds) The Focus for Pharmaceutical Knowledge. Palgrave, London. https://doi.org/10.1007/978-1-349-09571-1_23
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DOI: https://doi.org/10.1007/978-1-349-09571-1_23
Publisher Name: Palgrave, London
Print ISBN: 978-1-349-09573-5
Online ISBN: 978-1-349-09571-1
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