Abstract
In many respects, the subject of transmitter interactions recalls questions more than a decade old: how does one transmitter substance influence the responses of a cell to its other presumptive afferent transmitters. Such concerns were the obsessions of early iontophoretic experiments (see Bloom, 1974), when one sought patterns in the responsiveness to sets of transmitters as possibly significant attributes of specific neurons. The physiological response question then shifted to neurochemical and neuroanatomical determinants as to which transmitters and which source neurons a given target cell might normally need to recognize. Those data allowed us (see Foote et al., 1983; Siggins and Gruol, 1986) and others to evaluate synaptically released transmitters, rather than to deal with exogenously applied transmitter candidates. Many of the answers to those structural questions were provided by our hosts for this symposium, led by Dr. Fuxe and his collaborators.
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Bloom, F.E., Morrison, J., Battenberg, E., Lewis, D., Campbell, M. (1987). Interactions between Convergent Afferent Transmitter Systems. In: Fuxe, K., Agnati, L.F. (eds) Receptor-Receptor Interactions. Wenner-Gren Center International Symposium Series. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-08949-9_1
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DOI: https://doi.org/10.1007/978-1-349-08949-9_1
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