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Reverse Mutation in Salmonella typhimurium

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Comparative Genetic Toxicology
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Abstract

This laboratory participated in the Second UKEMS Collaborative Study, contributing to the work of the bacterial group. Our task was to test DAB and its analogue CDA, with both uninduced rat liver S9 and chicken liver S9. The test chemicals, S9 and bacterial cultures were provided by the study organisers, and we employed standard methods and experimental design as required. The results that we obtained are described below.

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Notes

  • Ames, B.N., McCann, J. and Yamasaki, E. (1975). Methods for detecting carcinogens and mutagens with the Salmonella/ mammalian-microsome test. Mutation Res. 31: 347–364

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  • Lefevre, P.A. and Ashby, J. (1981). The effects of preincubation period and norharman on the mutagenic potency of 4-dimethylaminoazobenzene and 3-methyl-4-dimethylaminoazobenzene in S. typhimurium. Carcinogenesis 2: 927–931

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© 1985 United Kingdom Environmental Mutagen Society

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Forster, R., Gwilliam, R.D. (1985). Reverse Mutation in Salmonella typhimurium . In: Parry, J.M., Arlett, C.F. (eds) Comparative Genetic Toxicology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07901-8_6

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