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Induction of Chromosome Aberrations in Chinese Hamster Liver Cells Treated with BZD, DAT, DAB and CDA

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Comparative Genetic Toxicology
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Summary

The effects of BZD, DAT, DAB and CDA (Sample A) on metaphase chromosomes of cultured Chinese hamster liver fibroblasts were studied. BZD and DAB induced high levels of aberrations while DAT and CDA induced smaller but still significant levels.

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Notes

  • Dean, B.J. and Hodson-Walker, G. (1979). An in vitro chromosome assay using cultured liver cells. Mutation Res. 64: 329–337

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  • Scott, D., Danford, N., Dean, B., Kirkland, D. (1983). In vitro chromosome aberration assays, in Report of the UKEMS Sub Committee on the Guidelines for Mutagenicity Testing, (ed. B.J. Dean), pp.41–64 Resolution: Global

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© 1985 United Kingdom Environmental Mutagen Society

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Lafi, A. (1985). Induction of Chromosome Aberrations in Chinese Hamster Liver Cells Treated with BZD, DAT, DAB and CDA. In: Parry, J.M., Arlett, C.F. (eds) Comparative Genetic Toxicology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07901-8_43

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