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Circadian Studies of Neurotransmitter Receptors

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Circadian Rhythms in the Central Nervous System

Abstract

The circadian nature of the release of hormones, such as cortisol is well established (Weitzman et al, 1971, 1975, for example) and there are several reports that CNS monoaminergic neurotransmitters undergo circadian changes in concentration and in rate of release (for example, see Martin and Marsden, this volume; Carlsson, 1980). In the pineal gland, circadian changes in synthesis of melatonin and in levels of hydroxyindole-o-methyltransferase are accompanied by changes in noradrenaline turnover, in β-adrenoceptor number and in the sensitivity of β-agonist-dependent cyclic AMP production (Axelrod and Zatz, 1977). Whether such circadian rhythms in receptor systems are restricted to tissues such as the pineal gland, which receive large circadian changes in neuronal input, or are a general phenomenon is the subject of this review.

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Reference

  • Axelrod, J. and Zatz, M. (1977), In Biochemical Actions of Hormones. IV, (ed. G. Litwack). Acad. Press, New York.

    Google Scholar 

  • Bylund, D. and U’Prichard, D.C. (1983). International Review. Neurobiol., 24, 343–431.

    CAS  Google Scholar 

  • Carlsson, A., Svennerholm, L. and Winblad, B. (1980). Acta Psychiatrica Scandinavia, 61, 5280, 75–85.

    CAS  Google Scholar 

  • Eiermann, S. (1983). PhD Thesis. Univ. of Basel.

    Google Scholar 

  • Greenberg, L. H. and Weiss, B. (1978). Science, 201, 61–63.

    Article  CAS  PubMed  Google Scholar 

  • Harden, T.K. (1983). Pharmac. Rev., 35(1), 5–32.

    CAS  Google Scholar 

  • Kafka, M.S., Wirz-Justice, A. and Naber, D. (1981). Brain Res., 207, 409–419.

    Article  CAS  PubMed  Google Scholar 

  • Kafka, M.S., Wirz-Justice, A., Naber, D., Marangos, P.J., O’Donohue, T.L., Wehr, T.A. (1982). Neuropsychobiol. 8, 41–50.

    Article  CAS  Google Scholar 

  • Kräuchi, K., Wirz-Justice, A., Morismasa, T., Willener, R. and Feer, H. (1984). Brain Res., 321, 83–90.

    Article  PubMed  Google Scholar 

  • Lefkowitz, R.J., Mulliken, D. and Caron, M.G. (1976). J. Biol.Chem., 251, 4686–4692.

    CAS  Google Scholar 

  • Leibowitz, S.F., Jhanwaruniyal, M. and Roland, C. R. (1984). Soc. for Neurosci. Abstr.

    Google Scholar 

  • Leibowitz, S.F. (1970). Proc. Nat. Acad. Sci. (USA). 67, 1063–1070.

    Article  CAS  Google Scholar 

  • Leibowitz, S.F. (1981). Psychopharmacol. Bull., 17, 59–66.

    CAS  Google Scholar 

  • Levitski, A. and Atlas, D. (1981). Life Sci., 28, 661–672.

    Article  Google Scholar 

  • McKernan, R.M. and Campbell, IC. (1982). Eur. J. Pharmac, 80 279–280.

    Article  CAS  Google Scholar 

  • Naber, D., Wirz-Justice, A. and Kafka, M.S. (1981). Neurosci. Lett. 21., 45–50.

    Article  CAS  PubMed  Google Scholar 

  • Reiter, R., Richardson, B.A. and Johnson, L.U. (1980). Science, 210, 1372–1373.

    Article  CAS  PubMed  Google Scholar 

  • Romero, J.A., Zatz, M., Kebabiar, J.W. and Axelrod, J. (1975). Nature (Lond.), 258, 435–436.

    Article  CAS  Google Scholar 

  • Romero, J.A. and Axelrod, J. (1974). Science, 184, 1091–1092.

    Article  CAS  PubMed  Google Scholar 

  • Strittmatter, W. J., Davis, J.N. and Lefkowitz, R.J. (1977). J. Biol.Chem., 252, 5478–5482.

    CAS  Google Scholar 

  • Wehr, T.A. and Wirz-Justice, A. (1982). Pharmacopsychiat., 15, 31–39.

    Article  CAS  Google Scholar 

  • Weitzman, E.D., Czeisler, CA., Zimmerman, J.D., Moore-Ede, M.C., Ronda, J.M. (1980). Trans. Am. Neurol. Assoc. 105, 371–374.

    CAS  Google Scholar 

  • Weitzman, E.D., de Graff, A.S., Sassen, J.F., Hansen, T., Godtlibsen, O.B., Perlow, M. and Hellman, L. (1975). Acta Eridocrinol. 78, 65–76.

    CAS  Google Scholar 

  • Weitzman, E.D., Enkushima, D., Nogeire, C., Roffwary, H., Gallagher, T.F. and Hellman, L. (1971). J. Clin. Endocrinol. Metab., 33, 14–22.

    Article  CAS  Google Scholar 

  • Wirz-Justice, A., Kafka, M.S., Naber, D. and Wehr, T.A. (1980). Life Sci., 27, 341–347.

    Article  CAS  PubMed  Google Scholar 

  • Wirz-Justice, A., Kräuchi, K. Campbell, I.C. and Feer, H. (1982). Brain Res., 262, 233–242.

    Article  Google Scholar 

  • Wirz-Justice, A., Naber, D., Moore, R.Y. and Benedito, M.A. (1983). Fed. Proc, 42, 2796–2801.

    PubMed  Google Scholar 

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Authors
  1. Iain C. Campbell
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  2. Anna Wirz-Justice
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  3. Kurt Kräuchi
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  4. Ruth M. McKernan
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  5. Michael J. Durcan
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Editor information

Editors and Affiliations

  1. Pharmacology Group, School of Pharmacy and Pharmacology, University of Bath, Bath, UK

    P. H. Redfern

  2. Institute of Psychiatry, London, UK

    I. C. Campbell

  3. Department of Pharmacology and Therapeutics, Welsh National School of Medicine, Cardiff, UK

    J. A. Davies

  4. Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, University of Nottingham, Nottingham, UK

    K. F. Martin

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© 1985 The Contributors

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Campbell, I.C., Wirz-Justice, A., Kräuchi, K., McKernan, R.M., Durcan, M.J. (1985). Circadian Studies of Neurotransmitter Receptors. In: Redfern, P.H., Campbell, I.C., Davies, J.A., Martin, K.F. (eds) Circadian Rhythms in the Central Nervous System. Satellite Symposia of the IUPHAR 9th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07837-0_7

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