Abstract
Metabolic and adjustive networks (Halberg et al., 1939, 1979a), as well as complementary networks for growth, repair and reproduction, are all characterized by interrcodulating rhythmic components of several orders and frequencies, A critical node in the interdigitating networks is the adrenal cortex, A spontaneous adrenal cortical cycle is preparatory to activity (Halberg, 1931, 1933; Halberg and Visscher, 1952; Halberg et al., 1951, 1953a, 1959) as well as responsive to factors from without (Pincus, 1943).
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Reference
Andrews, R.V. (1968). Temporal secretory responses of cultured hamster adrenals. Comp. Biochem. Physiol., 26, 179–193.
Andrews, R.V. (1971). Circadian rhythms in adrenal organ cultures. Gegenbaurs morph. Jahrb. Leipzig, 117, 89–98.
Assenmacher, I. (1982). CNS structures controlling circadian neuroendocrine and activity rhythms in rats. In Vertebrate Circadian Systems (eds. J. Aschoff, S. Daan and G.A. Groos). Springer-Verlag, Berlin, pp. 87–95.
Bartsch, H., and Bartsch, C. (1981). Effect of melatonin on experimental tumors under different photoperiods and times of administration. J. Neur. Trans., 52, 269–279.
Brown, G.M., Grota, L.J., Sanchez de la Pena, S., Halberg, F., and Halberg, E. (1983). Circadian melatonin rhythm: part of stimulatory feed-sideward in pineal modulation of adrenal response to ACTH 1–17? Minn. Acad. Sci., 51, 12.
Bryson, R.W., and Martin, D.F. (1954). 17-ketosteroid excretion in a case of manic-depressive psychosis. The Lancet, ii, 365–367.
Fabre, L.F. Jr, Banks, R.C., Mclsaac, W.M., and Farrell, G. (1965). Effects of ubiquinone and related substances on secretion of aldosterone and cortisol. Am. J. Physiol., 208, 1275–1980.
Farrell, G. (1959). Glomerulotropic activity of an acetone extract of pineal tissue. Endocrinol., 65, 239–241.
Galicich, J.H., Halberg, F., French, L.A., and Ungar, F. (1965). Effect of cerebral ablation on a circadian pituitary adrenocorticotropic rhythm in C mice. Endocr., 76, 895–901.
Günther, R., Herold, M., Halberg, E., Halberg, F. (1980). Circadian placebo and ACTH effects on urinary cortisol in arthritics. Peptides, 1, 387–390.
Halberg, F. (1951). Discussion remarks. In: Proc. 2nd Clinical ACTH Conference, Vol. 1: Research (ed. J.R. Mote). Blakiston, New York, pp. 84–86.
Halberg, F. (1953). Some physiological and clinical aspects of 24-hour periodicity. J. Lancet (USA), 73, 20–32.
Halberg, F. (1959). Physiologic 24-hour periodicity; general and procedural considerations with reference to the adrenal cycle. Z. Vit.-, Hormon- u. Fermentforsch. 10, 225–296.
Halberg, F. (1960a). Temporal coordination of physiologic function. Cold Spr. Harb. Symp. quant. Biol., 25, 289–310.
Halberg, F. (1960b). Symposium on ‘Some current research methods and results with special reference to the central nervous system’. Physiopathologic approach. Am. J. ment. Defic, 65, 156–171.
Halberg, F. (1968). Physiologic considerations underlying rhythmometry, with special reference to emotional illness. Symposium on Biological Cycles and Psychiatry. In: Symposium Bel-Air III, Geneva, Masson et Cie., pp. 73–126.
Halberg, F. (1982). Quantitative chronobiology and psychoneuroendocrinology. In Brain, Peptides and Hormones, Proc. XII Cong. Int. Soc. Psychoneuroendocrinol., Montreal, May 25–28, 1981 (eds. R. Collu, A. Barbeau, J.R. Ducharme, G. Tolis). Raven Press, New York, pp. 241–256.
Halberg, F. (1983). Quo vadis basic and clinical chronobiology: promise for health maintenance. Am. J. Anat., 168, 543–594.
Halberg, F., Barnum, C.P., Silber, R.H. and Bittner, J.J. (1958a). 24-hour rhythms at several levels of integration in mice on different lighting regimens. Proc. Soc. exp. Biol. Med., 97, 897–900.
Halberg, F., Cornelissen G., Sothern R.B., Wallach L.A., Halberg E., Ahlgren, A., Kuzel, M., Radke, A., Barbosa, J., Goetz, F., Buckley, J., Mandel, J., Schuman, L., Haus, E., Lakatua, D., Sackett, L., Berg, H., Wendt, H.W., Kawasaki, T., Ueno, M., Uezono, K., Matsuoka, M., Oraae, T., Tarquini, B., Cagnoni, M., Garcia Sainz, M., Perez Vega, E., Wilson, D., Griffiths, K., Donati, L., Tatti, P., Vasta, M., Locatelli, I., Camagna, A., Lauro, R., Tritsch, G., Wetterberg, L. (1981). International geographic studies of oncological interest on chronobiological variables. In Neoplasms—Comparative Pathology of Growth in Animals, Plants and Man(ed. H. Kaiser). Williams and Wilkins, Baltimore, pp. 553–596.
Halberg, F., Engeli, M., Hamburger, C., and Hillman, D. (1965). Spectral resolution of low-frequency, small-amplitude rhythms in excreted 17-ketosteroid; probable androgen-induced circaseptan desynchronization. Acta endocr. (Kbh.), Suppl. 103, 5–54.
Halberg, F., French, L.A., Gully, R.J. (1958b). 24-hour rhythms in rectal temperature and blood eosinophils after hemidecortication in human subjects. J. appl. Physiol., 12, 381–384.
Halberg, F., Gupta, B.D., Haus, E., Halberg, E., Deka, A.C., Nelson, W.L., Sothern, R.B., Cornelissen, G., Lee, J.K., Lakatua, D.J., Scheving, L.E., and Burns, E.R. (1977). Steps toward a cancer chronopolytherapy. In Proceedings, XIV Int. Congress on Therapeutics, Montpellier, France, L’Expansion Scientifique Française, pp. 151–196.
Halberg, F., Halberg, E., Barnum, C.P., and Bittner, J.J. (1959). Physiologic 24-hour periodicity in human beings and mice, the lighting regimen and daily routine. In Photoperiodism and Related Phenomena in Plants and Animals (ed. R.B. Withrow). Publ. #55, Am. Assoc. Adv. Sci., Washington, DC, pp. 803–878.
Halberg, F., Halberg, E., and Carandente, F. (1976). Chronobiology and metabolism in the broader context of timely intervention and timed treatment. Diabetes Research Today, Meeting of the Minkowski Prize Winners, Symposia Medica Hoechst 12 (Capri), F.K. Schattauer Verlag, Stuttgart/New York, pp. 45–95.
Halberg, F., Halberg, E., Halberg, J. (1979a). Collateral-interacting hierarchy of rhythm coordination at different organization levels, changing schedules and aging. In Biological Rhythms and their Central Mechanism (eds. M. Suda, O. Hayaishi and H. Nakagawa). Elsevier North-Holland Biomedical Press, Amsterdam, pp. 421–434 (cf. also discussion pp. 435–438).
Halberg, F., Lubanovic, W.A., Sothern, R.B., Brockway, B., Powell, E.W., Pasley, J.N., Scheving, L.E. (1979b). Nomifensine chronopharmacology, schedule shifts and circadian temperature rhythm in di-suprachiasmatically-lesioned rats: modeling emotional chronopathology and chronotherapy. Chronobiologia, 6, 405–424.
Halberg, F., and Visscher, M.B. (1952). A difference between the effects of dietary calorie restriction on the estrous cycle and on the 24-hour adrenal cortical cycle in rodents. Endocrinology, 51, 329–335.
Halberg, F., Visscher, M.B., Flink, E.B., Berge, K., and Bock, F. (1951). Diurnal rhythmic changes in blood eosinophil levels in health and in certain diseases. J. Lancet, 71, 312–319.
Haus, E., and Halberg, F. (1980). Endocrine rhythms. In Chrono-biology: Principles and Applications to Shifts in Schedules (eds. L.E. Scheving and F. Halberg). Sijthoff and Noordhoff, Alphen aan den Rijn, pp. 137–188.
Haus, E., Halberg, F., Sothern, R.B., Lakatua, D., Scheving, L.E., Sánchez de la Pena, S., Sanchez, E., Melby, J., Wilson, T., Brown, H., Berg, H., Levi, F., Culley, D., Halberg, E., Hrushesky, W., Pauly, J. (1980). Time-varying effects in mice and rats of several synthetic ACTH preparations. Chronobiologia, 7, 211–226.
Hayes, D.K., Halberg, F., Cornelissen, G., and Stebbings, J.H. (1981). Chronobiologic concepts and biomathematical methods applicable to design and analyses of time series studies of human health. Proc. Environmetrics 81, Summaries of Conference Presentations, SIAM, pp. 318–319.
Heiman, M.L., and Porter, J.R. (1980). Inhibitory effects of a pineal extract on adrenal cortex: lack of competition with ACTH. Hormone Res., 12, 104–112.
Hermida Dominguez, R.C., Halberg, F., Halberg, E., and Del Pozo, F. (1982). Toward a psychoneuroendocrine hemopsy. Clin. Chem. News., 2, 191–198.
Krieger, D.T., and Allen, W. (1975). Relationship of bioassayable and immunoassayable plasma ACTH and cortisol concentrations in normal subjects and in patients with Cushing’s disease. J. Clin. Endocr. Metab., 40, 675–687.
Lang, U., Aubert, M.L., and Sizonenko, P.C. (1981). Tissue distribution and subcellular location of melatonin receptors in the male rat. Experientia, 37, 613.
Langevin, T., Hrushesky, W., Sanchez, S., Halberg, F. (1983). Melatonin (M) modulates survival of CD2F1 mice with L1210 leukemia. Chronobiologia, 10, 173–174.
Levi, F., Halberg, F., Nesbit, M., Haus, E., Levine, H. (1981). Chrono-oncology. In Neoplasms—Comparative Pathology of Growth in Animals, Plants and Man (ed. H. Kaiser). Williams and Wilkins, Baltimore, pp. 267–312.
Levine, H., Ramshaw, W.A., and Halberg, F. (1967). Least squares spectral analyses on core temperature and blood pressure of a comatose girl. The Physiologist, 10, 230.
Moore, R.Y. (1979). The retinohypothalamic tract, suprachiasmatic hypothalamic nucleus and central neural mechanisms of circadian rhythm regulation. In Biological Rhythms and their Central Mechanism (eds. M. Suda, O. Hayaishi and H. Nakagawa). Elsevier/North-Holland Biomédical Press, Amsterdam, pp. 343–54.
Moser, P.C., and Redfern, P.H. (1984). Diurnal variation in behavioural responses to 5-HT receptor stimulation. Brit. J. Pharmacol., 82, 269–270.
Passouant P., Halberg, F., Genicot, R., Popoviciu, L., Baldy-Moulinier, M. (1969). La périodicité des accès narcoleptiques et le rythme ultradien du sommeil rapide. Rev. neurol. (Paris), 121, 155–164.
Pedersen, R.C., Brownie, A.C., and Ling, N. (1980). Pro-adrenocorticotropin/endorphin derived peptides: coordinate action on adrenal steroidogenesis (16K fragment & MSH). Science, 208, 1094–1095.
Pincus, G. (1943). A diurnal rhythm in the excretion of urinary ketosteroids by young men. J. Clin. Endocrinol. 3, 195.
Porter, J.R., and Heiman, M. (1977). The effects of pineal indoles and a crude aqueous pineal extract on ACTH-mediated corticosterone release by isolated adrenal cells. Life Sci. 20, 1363.
Quay, W.B. (1974). Pineal Chemistry in Cellular and Physiological Mechanisms. Charles C. Thomas, Springfield, I11.
Sánchez de la Peña, S., Halberg, F., Haus, E., Lakatua, D., Halberg, E., and Ungar, F. (1984a). Circadian modulation by melatonin of murine ACTH secretion and corticosterone production in vitro. 7th Int. Cong. Endocrinol., July 1–7, 1984, Quebec, Canada, abstract #2122, p. 1321.
Sanchez de la Peña, S., Halberg, F., Schweiger, H.-G., Eaton, J., and Sheppard, J. (1984b). Circadian temperature rhythm and circadian-circaseptan (about-7-day) aspects of murine death from malaria. Proc. Soc. exp. Biol. Med. 175, 196–204.
Sánchez de la Peña, S., Halberg, F., and Ungar, F. (1982). Pineal chronomodulation—the feed-sideward. Clin. Chenu Newsletter 2, 129–130.
Sánchez de la Peña, S., Halberg, F., Halberg, E., Ungar, F., Cornelissen, G., Sánchez, E., Brown, G., Yunis, E.G., Vecsei, P. (1983a). Pineal modulation of ACTH 1–17 effect upon murine corticosterone production. Brain Res. Bull., 11, 117–125.
Sánchez de la Peña, S., Halberg, F., Ungar, F., Haus, E., Lakatua, D., Scheving, L.E., Sánchez, E., Vecsei, P. (1983b). Circadian pineal modulation of pituitary effect on murine corticosterone in vitro. Brain Res. Bull., 10, 559–565.
Scheving, L.E. (1976). The dimension of time in biology and medicine—chronobiology. Endeavour, 35, 66–72.
Scheving, L.E., Tsai, T.H., Powell, E.W., Pasley, J.N., Halberg, F., and Dunn, J. (1983). Bilateral lesions of suprachiasmatic nuclei affect circadian rhythms in [3H]thymidine incorporation into deoxyribonucleic acid in mouse intestinal tract, mitotic index of corneal epithelium, and serum corticsterone. Anat. Rec., 205, 239–249.
Schweiger, H.-G., and Halberg, F. (1982). Can a unicell measure the week and an isolated cytoplasm measure half a week? Notiziario SIBioC, 6, 525–526.
Szafarczyk, A., Ixart, G., Malaval, F., Nouguier-Soule, J., and Assenmacher, I. (1979). Effects of lesions of the suprachiasmatic nuclei and of p-chlorophenylalanine on the circadian rhythms of adrenocorticotropic hormone and corticosterone in the plasma, and on locomotor activity of rats. J. Endocr., 83, 1–16.
Ungar, F., and Halberg, F. (1963). In vitro exploration of a circadian rhythm in adrenocorticotropic activity of C mouse hypophysis. Experientia 19, 158–159.
Vollrath, L. (1982). Circadian and infradian activity rhythms in the mammalian pineal body. In Vertebrate Circadian Systems (eds. J. Aschoff, S. Daan, and G.A. Groos). Springer-Verlag, Berlin, pp. 141–146.
Vollrath, L., Kantarjian, A., and Howe, C, (1974). Mammalian pineal gland: 7-day rhythmic activity? Experientia, 31, 458–460.
Walker, W.V., Russell, J.E., Simmons, D.J., Scheving, L.E., Corne-lissen G., and Halberg, F. (in press). Effect of an adreno-corticotropin analogue, ACTH 1–17, on DNA synthesis in murine metaphyseal bone. J. Biochem. Pharm.
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Halberg, F., de la Peña, S.S., Cornelissen, G. (1985). Circadian Adrenocortical Cycle and the Central Nervous System. In: Redfern, P.H., Campbell, I.C., Davies, J.A., Martin, K.F. (eds) Circadian Rhythms in the Central Nervous System. Satellite Symposia of the IUPHAR 9th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07837-0_5
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