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Purines pp 27–44Cite as

Palgrave Macmillan

Behavioral Actions of Adenosine Analogues

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Abstract

In recent years it has become increasingly clear that brain function and therefore behavior cannot be understood simply in terms of the “hard-wiring” circuitry in the nervous system. The integrative capacity of the nervous system must accrue from the enormous variability of the intercellular transmission process between neurons. Furthermore, it is now evident that not only is the transmission process of central neurons extraordinarily varied but so is the chemical vocabulary by which neurons communicate. There has been considerable recent evidence, primarily from histo-chemistry, release and uptake studies, that transmitter-like molecules may co-exist in certain vertebrate neurons (Osborne, 1981). However, the fact that a neuron contains several putative transmitter substances, does not establish that each substance is being released as a transmitter. It certainly is possible that some neurons release more than one type of transmitter substance from the same terminal wherein only one of these would serve as the primary neurotransmitter with the others functioning to modify or modulate the action of the primary neurotransmitter.

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Authors
  1. Robin A. Barraco
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Editor information

Editors and Affiliations

  1. Department of Physiology, St George’s Hospital Medical School, SW17 0RE, London, UK

    T. W. Stone

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© 1985 The Contributors

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Barraco, R.A. (1985). Behavioral Actions of Adenosine Analogues. In: Stone, T.W. (eds) Purines. Satellite Symposia of the IUPHAR 9th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07564-5_4

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