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D-1 Dopamine Receptor Stimulation Increases, and D-2 Dopamine Receptor Stimulation Decreases, the Excitability of Growth Hormone Producing Cells in the Snail Lymnaea stagnalis

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Dopaminergic Systems and their Regulation

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Abstract

Dopamine (DA) induces biochemical and physiological effects in the mammalian central nervous system (CNS). The occurrence of a D-1 dopamine receptor (in the classification scheme of Kebabian and Calne, 1979) accounts for the ability of DA to enhance cyclic AMP formation. The occurrence of a D-2 dopamine receptor accounts for the ability of DA to inhibit cyclic AMP formation brought about by stimulation of a D-1 receptor (Stoof and Kebabian, 1981). This categorization of DA-receptors is currently accepted by most investigators.

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References

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Author information

Authors and Affiliations

  1. Departments of Neurology and Biology, Free University, Amsterdam, Netherlands

    J. C. Stoof, Th. A. de Vlieger & J. C. Lodder

Authors
  1. J. C. Stoof
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  2. Th. A. de Vlieger
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  3. J. C. Lodder
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Editor information

Editors and Affiliations

  1. Merck Sharp and Dohme Research Laboratories, Harlow, Essex, UK

    G. N. Woodruff (Director of Pharmacology) (Director of Pharmacology)

  2. Department of Physiology and Pharmacology, University of Southampton, UK

    J. A. Poat  & P. J. Roberts  & 

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© 1986 The Contributors

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Stoof, J.C., de Vlieger, T.A., Lodder, J.C. (1986). D-1 Dopamine Receptor Stimulation Increases, and D-2 Dopamine Receptor Stimulation Decreases, the Excitability of Growth Hormone Producing Cells in the Snail Lymnaea stagnalis . In: Woodruff, G.N., Poat, J.A., Roberts, P.J. (eds) Dopaminergic Systems and their Regulation. Satellite Symposia of the IUPHAR 9th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07431-0_44

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  • DOI: https://doi.org/10.1007/978-1-349-07431-0_44

  • Publisher Name: Palgrave Macmillan, London

  • Print ISBN: 978-1-349-07433-4

  • Online ISBN: 978-1-349-07431-0

  • eBook Packages: MedicineMedicine (R0)

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