Abstract
It is a particular privilege to join in this symposium honoring Yngve Zotterman. His gracious hospitality and enthusiasm for science was an inspiration to me as to so many others. My invitation asked for an overview for the presentations to follow in this session, a rather difficult task because of the scope of the topics involved. I have chosen instead to offer a theory about a feature of the organization of the somatosensory system that touches on the several topics, with the realization that while speculation in science is a precarious game, it would have pleased Yngve Zotterman; he loved to practice it.
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References
Andersson, S.A., Landgren, S. and Wolsk, D. (1966). The thalamic relay and cortical projection of group I muscle afferents from the forelimb of the cat. J. Physiol., Lond., 183, 576–591.
Angaut-Petit, D. (1975a). The dorsal column system: I. Existence of long ascending postsynaptic fibres in the cat’s fasciculus gracilis. Expl. Brain Res., 22, 457–470.
Angaut-Petit, D. (1975b). The dorsal column system: II. Functional properties and bulbar relay of the postsynaptic fibres of the cat’s fasciculus gracilis. Expl. Brain Res., 22, 471–493.
Bessou, P. and Perl, E.R. (1969). Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J. Neurophysiol., 32, 1025–1043.
Boivie, J.J.G. and Perl, E.R. (1975). Neural substrates of somatic sensation. In Neurophysiology I. (ed. C.C. Hunt). University Park, Baltimore.
Brown, A.G. (1973). Ascending and long spinal pathways: dorsal columns, spinocervical tract and spinothalamic tract. In Handbook of Sensory Physiology. Somatosensory System. (ed. A. Iggo). Springer-Verlag, Berlin.
Brown, A.G. (1981). Organization in the Spinal Cord. Springer-Verlag, Berlin.
Brown, A.G., Hamann, W.C. and Martin, H.F., III. (1975). Effects of activity in non-myelinated afferent fibres on the spinocervical tract. Brain Res., 98, 243–259.
Brown, A.G. and Iggo, A. (1967). A quantitative study of cutaneous receptors and afferent fibres in the cat and rabbit. J. Physiol., Lond., 193, 707–733.
Burgess, P.R. and Perl, E.R. (1973). Cutaneous mechanoreceptors and nociceptors. In Handbook of Sensory Physiology. Somatosensory System. (ed. A. Iggo). Springer-Verlag, Berlin.
Chung, J.M., Kenshalo, D.R., Jr., Gerhart, K.D. and Willis, W.D. (1979). Excitation of primate spinothalamic neurons by cutaneous C-fiber volleys. J. Neurophysiol., 42, 1354–1369.
Frey, M. von. (1897). Beiträge zur Sinnesphysiologie der Haut (Part IV). Koenigl. Saechs. Ges. Wiss., Math.-Phys. Klasse, 49, 462–468.
Guilbaud, G. (1983). Organization of noxious and non-noxious inputs in SmI cortex: comparison in normal and in arthritic rats. Presentation at symposium on Somatosensory Mechanisms held at Stockholm, Sweden, June 8–10, 1983. Published in this volume.
Honda, C.N., Mense, S. and Perl, E.R. (1983). Neurons in ventrobasal region of cat thalamus selectively responsive to noxious mechanical stimulation. J. Neurophysiol., 49, 662–673.
Iggo, A. (1980). Presentation at Satellite Symposium of the International Congress of Physiological Sciences held at Keszthely, Hungary, July 9–12, 1980.
Kenshalo, D.R., Jr., Leonard, R.B., Chung, J.M. and Willis, W.D. (1979). Responses of primate spinothalamic neurons to graded and to repeated noxious stimuli. J. Neurophysiol., 42, 1370–1389.
Kenshalo, D.R., Jr., Giesler, G.J., Jr., Leonard, R.B. and Willis, W.D. (1980). Responses of neurons in primate ventral posterior lateral nucleus to noxious stimuli. J. Neurophysiol., 43, 1594–1614.
Kenshalo, D.R., Jr., and Isensee, O. (1983). Effects of noxious stimuli on primate SI cortical neurons. In Advances in Pain Research and Therapy. (eds. J.J. Bonica, U. Lindblom and A. Iggo). Raven Press, New York.
Kniffki, K.-D. and Mizumura, K. (1983). Responses of neurons in VPL and VPL-VL region of the cat to algesic stimulation of muscle and tendon. J. Neurophysiol., 49, 649–661.
Kumazawa, T., Perl, E.R., Burgess, P.R. and Whitehorn, D. (1975). Ascending projections from marginal zone (lamina I) neurons of the spinal dorsal horn. J. Comp. Neurol., 162, 1–11.
Lundberg, A. and Oscarsson, O. (1962). Two ascending spinal pathways in the ventral part of the cord. Acta physiol. scand., 54, 270–286.
Magoun, H.W. and Rhines, R. (1947). Spasticity — The Strength Reflex and Extra-Pyramidal Systems. Charles C. Thomas, Springfield, Ill.
Mayer, D.J., Price, D.D. and Becker, D.P. (1975). Neurophysiological characterization of the anterolateral spinal cord neurons contributing to pain perception in man. Pain, 1, 51–58.
Melzack, R. and Wall, P.D. (1962). On the nature of cutaneous sensory mechanisms. Brain, 85, 331–356.
Müller, J. (1840). Handbuch der Physiologie des Menschen. J. Hölscher, Coblenz.
Müller, J. (1842). Elements of Physiology. Taylor and Walton, London.
Perl, E.R., Whitlock, D.G. and Gentry, J.R. (1961). Cutaneous projection to second-order neurons of the dorsal column system. J. Neurophysiol., 25, 337–358.
Poggio, G.F. and Mountcastle, V.B. (1960). A study of the functional contributions of the lemniscal and spinothalamic systems to somatic sensibility. Bull. Johns Hopkins Hosp., 106, 266–316.
Poggio, G.F. and Mountcastle, V.B. (1963). The functional properties of ventrobasal thalamic neurons studied in unanesthetized monkeys. J. Neurophysiol., 26, 775–806.
Rastad, J., Jankowska, E. and Westman, J. (1977). Arborization of initial axon collaterals of spinocervical tract cells stained intracellularly with horseradish peroxidase. Brain Res., 135, 1–10.
Rose, J.E. and Mountcastle, V.B. (1959). Touch and kinesthesis. In Handbook of Physiology, Section 1 — Neurophysiology, v. 1. (eds. J. Field and H.W. Magoun). American Physiological Society, Washington, D.C.
Rustioni, A. (1973). Non-primary afferents to the nucleus gracilis from the lumbar cord of the cat. Brain Res., 51, 81–95.
Sinclair, D.C. (1955). Cutaneous sensation and the doctrine of specific energy. Brain, 78, 584–614.
Trevino, D.L., Coulter, J.D. and Willis, W.D. (1973). Location of cells of origin of spinothalamic tract in lumbar enlargement of the monkey. J. Neurophysiol., 36, 750–761.
Uddenberg, N. (1968). Functional organization of long, secondorder afferents in the dorsal funiculus. Expl. Brain Res., 4, 377–382.
Willis, W.D. (1982). Control of nociceptive transmission in the spinal cord. In Progress in Sensory Physiology 3. (ed. D. Ottoson). Springer-Verlag, Berlin.
Witt, I. and Hensel, H. (1959). Afferente Impulse aus der Extremitätenhaut der Katze bei thermischer und mechanischer Reizung. Pflügers Arch. ges. Physiol., 268, 582–596.
Zotterman, Y. (1939). Touch, pain and tickling: an electrophysiological investigation on cutaneous sensory nerves. J. Physiol., Lond., 95, 1–28.
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© 1984 The Wenner-Gren Center
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Perl, E.R. (1984). Why are Selectively Responsive and Multireceptive Neurons both Present in Somatosensory Pathways?. In: von Euler, C., Franzén, O., Lindblom, U., Ottoson, D. (eds) Somatosensory Mechanisms. Wenner-Gren Center International Symposium Series. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07292-7_9
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