Cutaneous Thermoreceptors

Part of the Wenner-Gren Center International Symposium Series book series (WGS)


The discovery by Yngve Zotterman (1935, 1936) that afferent fibres in the lingual nerve respond to changes in temperature of the surface of the tongue, was an important landmark in the study of somatosensory mechanisms. It is a pleasure on this occasion to recall the excitement with which Yngve would recount the circumstances of the discovery, since he was actually investigating the peripheral mechanisms of taste at the time, and probably found the action potentials evoked by his sapid and probably cool solutions, but actually generated in thermoreceptors, to be a great inconvenience.


Skin Temperature Afferent Fibre Adrenal Vein Cold Receptor Interburst Interval 
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  1. Anand, Ashima., Iggo, A. & Paintal, A.S. (1982). Genesis of the ‘burst’ discharge in primate cutaneous cold receptors. J.Physiol., 327, 66–67P.CrossRefGoogle Scholar
  2. Blix, M. (1882). Experimentela bidrag till lösning af frågan om hudnervernas specifika energi. I. Uppsala Läkare Förening Förehandlinger, 18, 87–102.Google Scholar
  3. Braun, H.A., Bade, H. & Hensel, H. (1980). Static and dynamic discharge of bursting cold fibers related to hypothetical receptor mechanisms. Pflüg. Arch. ges. Physiol., 386, 1–9.CrossRefGoogle Scholar
  4. Hensel, H. (1953). Das verhalten der Thermoreceptoren bei Ischämie. Pflug. Arch. ges. Physiol., 257, 371–383.CrossRefGoogle Scholar
  5. Hensel, H. (1981). Thermoreception and temperature regulation. Monographs of the Physiological Society No. 38. Academic Press, London.Google Scholar
  6. Hensel, H. & Boman, K.K.A. (1960). Afferent impulses in cutaneous sensory nerves in human subjects. J.Neurophysiol. 23, 564–578.PubMedGoogle Scholar
  7. Hensel, H. & Zotterman, Y. (1951a). The response of the cold receptors to constant cooling. Acta physiol. scand., 22, 96–113.CrossRefPubMedGoogle Scholar
  8. Hensel, H. & Zotterman, Y. (1951b). Quantitative Beziehungen zwischen der Engladung einzelner Kältefasern und der Temperatur. Acta physiol. scand., 23, 291–319.CrossRefPubMedGoogle Scholar
  9. Hensel, H. & Zotterman, Y. (1951c). Action potentials of cold fibres and intracutaneous temperature gradient. J. Neurophysiol., 14, 377–385.PubMedGoogle Scholar
  10. Iggo, A. (1958). The electro physiological identification of single nerve fibres, with particular reference to the slowest conducting vagal afferent fibres in the cat. J.Physiol., 142, 110–126.CrossRefPubMedPubMedCentralGoogle Scholar
  11. Iggo, A. (1969). Cutaneous thermoreceptors in primates and subprimates. J.Physiol., 200, 403–430.CrossRefPubMedPubMedCentralGoogle Scholar
  12. Iggo, A. & Iggo, B.J. (1971). Impulse coding in primate cutaneous thermoreceptors in dynamic thermal conditions. J.Physiol. (Paris), 63, 287–290.Google Scholar
  13. Iggo, A. & Paintal, A.S. (1977). The metabolic dependence of primate cutaneous cold receptors. J.Physiol., 272, 40–41P.Google Scholar
  14. Iggo, A. & Young, D.W. (1975). Cutaneous thermoreceptors and thermal nociceptors. In The Somatosensory System. (ed. H.H. Kornhuber). Thieme, Stuttgart. pp. 5–22.Google Scholar
  15. Long, Randall, R. (1977). Sensitivity of cutaneous cold fibers to noxious heat: paradoxical cold discharge. J.Neurophysiol., 40, 489–502.PubMedGoogle Scholar
  16. Pierau, F-K., Torrey, P. & Carpenter, D.O. (1975). Mammalian cold receptor afferents: role of an electrogenic sodium pump in sensory transduction. Brain Res., 73, 156–160.CrossRefGoogle Scholar
  17. Pierau, F-K., Torrey, P. & Carpenter, D. (1975). Effect of Ouabain and potassium-free solution on mammalian thermosensitive afferents in vitro. Pflüg. Arch. ges. Physiol., 359, 349–356.CrossRefGoogle Scholar
  18. Pierau, Fr.-K., Ullrich, J. & Wurster, R.D. (1977). Effect of Ca++ and EDTA on the bursting pattern of lingual cold receptors in cats. Proc.Int. Union physiol.Sci. 13, 597.Google Scholar
  19. Zotterman, Y. (1935). Action potentials in the glossopharyngeal nerve and in the chorda tympani. Skand. Arch.Physiol. 72, 73–77.CrossRefGoogle Scholar
  20. Zotterman, Y. (1936). Specific action potentials in the lingual nerve of the cat. Skand. Arch. Physiol. 75, 105–119.CrossRefGoogle Scholar

Copyright information

© The Wenner-Gren Center 1984

Authors and Affiliations

  • A. Iggo
    • 1
  1. 1.Department of Veterinary PhysiologyUniversity of EdinburghUK

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