Agarose-Based Haemoperfusion Columns For The Removal Of Excess Ldl-cholesterol From Whole Blood
Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterised by elevated levels of low density lipoprotein cholesterol (LDL-C), tendon xanthomas and premature coronary atherosclerosis (Mabuchi et al., 1983). This abnormality is inherited as an incompletely dominant strain, resulting in a deficiency of cell surface receptors and defective binding of low density lipoprotein (LDL) to these receptors (Goldstein et al., 1975).
KeywordsCholesterol Acetone Albumin Urea Agarose
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