Abstract
Controlled clinical trials usually compare a fixed dose of a drug x with either a placebo or a fixed dose of a reference drug. In the first case, the question to be answered is: ‘Is x an efficient drug?’ In the second case: ‘Is x more (or equally, or less) efficient than the reference drug?’
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Simon, P., Landragin, L., Puech, A.J., Lecrubier, Y. (1983). Practical aspects of the utilization of double-blind trials using adjusted doses of psychotropic drugs. In: Gram, L.F., Usdin, E., Dahl, S.G., Kragh-Sørensen, P., Sjöqvist, F., Morselli, P.L. (eds) Clinical Pharmacology in Psychiatry. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-06671-1_6
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DOI: https://doi.org/10.1007/978-1-349-06671-1_6
Publisher Name: Palgrave Macmillan, London
Print ISBN: 978-1-349-06673-5
Online ISBN: 978-1-349-06671-1
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