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Modified nucleosides from transfer ribonucleic acid as tumor markers

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Biochemistry of S-Adenosylmethionine and Related Compounds

Abstract

Among the various nucleic acids, tRNA is the one which contains the highest and most varied number of modified nucleosides. Up to 15 of them have been found in a single molecule of eukaryotic tRNA with pseudouridine present up to 25% and the methylated nucleosides varying between 30% and 70% (see Agris, 1980).

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References

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Cimino, F., Costanzo, F., Russo, T., Colonna, A., Esposito, F., Salvatore, F. (1982). Modified nucleosides from transfer ribonucleic acid as tumor markers. In: Biochemistry of S-Adenosylmethionine and Related Compounds. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-06343-7_56

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