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Assessment of Extrapyramidal Disorders

  • Chapter
Methods in Clinical Pharmacology—Central Nervous System

Abstract

In the last twenty years the accurate evaluation of extrapyramidal disorders has become essential to assess the efficacy of an increasing number of potentially useful drugs. Not surprisingly, since the introduction of levodopa, Parkinson’s disease has attracted the most attention for developing assessment techniques. It is a common condition, producing a complex and varying pattern of disabilities, and effective treatment is available with which new drugs may be compared. Techniques suitable for use in patients with Parkinson’s disease are applicable also to patients with other akinetic-rigid syndromes, but different methods have to be employed to assess the severity and impact of other extrapyramidal diseases which cause abnormal involuntary movements (dyskinesias). The many types and causes of the extrapyramidal disorders under consideration are shown in Table 1.

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Authors and Affiliations

  1. Institute of Psychiatry and King’s College Hospital Medical School, University Department of Neurology, Denmark Hill, London, SE5, UK

    C. D. Marsden & M. Schachter

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  1. C. D. Marsden
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  2. M. Schachter
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M. H. Lader A. Richens

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© 1981 Palgrave Macmillan, a division of Macmillan Publishers Limited

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Marsden, C.D., Schachter, M. (1981). Assessment of Extrapyramidal Disorders. In: Lader, M.H., Richens, A. (eds) Methods in Clinical Pharmacology—Central Nervous System. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-06038-2_8

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