Abstract
Quinoxaline antibiotics are of widespread occurrence in nature. They are produced by a variety of species of streptomycetes and are characterised by an octadepsipeptide ring to which are attached two moieties of quinoxaline-2-carboxylic acid, hence their name. They were first isolated in the 1950s (see Katagiri et al., 1975 for a full description) and the best-known member of the group is echinomycin (Corbaz et al., 1957; Keller-Schierlein et al., 1959) whose structure, shown in figure 1, was recently revised.
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Waring, M.J., Fox, K.R. (1983). Molecular Aspects of the Interaction between Quinoxaline Antibiotics and Nucleic Acids. In: Neidle, S., Waring, M.J. (eds) Molecular Aspects of Anti-Cancer Drug Action. Topics in Molecular and Structural Biology. Palgrave, London. https://doi.org/10.1007/978-1-349-06010-8_5
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DOI: https://doi.org/10.1007/978-1-349-06010-8_5
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