Controversies in the Clinical Evaluation of Antifertility Plants

  • R. R. Chaudhury

Abstract

The controversies, challenges and problems that arise when carrying out clinical trials of plants with antifertility properties can be appreciated better if viewed against, a) a background of the historical use of medicinal plants, b) the past experience in screening of such plants for pharmacological activity and c) an understanding of some of the relevant concepts of the indigenous systems of medicine where plants have been traditionally utilized.

Keywords

Toxicity Estrogenic Fractionation Histamine Prostaglandin 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Biswas, K. (1955). Cultivation of Rauwolfia in West Bengal. Proceedings of the symposium on Rauwolfia, October, 1955. C.S.I.R.Google Scholar
  2. Chaudhury, R. R. & Vohra, S. B. (1970). Indigenous antifertility plants. In Advances in Research in Indian Medicine. Varanasi: Banaras Hindu University.Google Scholar
  3. Garg, S. K., Mathur, V. S. & Chaudhury, R. R. (1978). Screening of Indian plants for antifertility activity. Ind. J. exp. Biol., 16, 1077.Google Scholar
  4. Garg, S. K., Vohra, S. B. & Chaudhury, R. R. (1969). Investigations on Butea monosperma (Lam) Kuntze. Ind. J. med. Res., 57, 1946.Google Scholar
  5. Indian Council of Medical Research (1980). Policy statement on ethical considerations involved in research on human subjects. New Delhi.Google Scholar
  6. Landgren, B. M., Aedo, A. R., Hagenfeldt, K. & Diczfalusy, E. (1979). Clinical effects of orally administered extracts of Montana tomentosa in early human pregnancy. Am. J. Obst. Gynec., 135, 480–484.Google Scholar
  7. Meharji, P. K., Shetye, T. A., Munshi, S. R., Vaidya, R. A., Antaskar, D. A., Koppikar, S. & Devi, P. K. (1978). Screening of Mesua Ferrea (Nagkesar) for estrogenic and progestational activity in human and experimental models. Ind. J. exp. Biol., 16, 932–933.Google Scholar
  8. Soejarto, D. D., Bingel, A. S., Slaytor, M. & Farnsworth, N. R. (1978). Fertility regulating agents from plants. Bull. WHO, 56, 343.PubMedCentralPubMedGoogle Scholar

Copyright information

© The contributors 1980

Authors and Affiliations

  • R. R. Chaudhury
    • 1
  1. 1.Department of PharmacologyPostgraduate Institute of Medical Education and ResearchChandigarhIndia

Personalised recommendations