Abstract
As has been discussed in other papers in this section, patients with essential hypertension exhibit widely different sensitivities to antihypertensive drugs, and this diversity is only partly explained in terms of varying bio-availability and pharmocokinetics.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Birkenhäger, W. H., de Leeuw, P. W., Kho, T. L., Wester, A., Vandongen, R. & Falke, H. E. (1977). Selection of hypertensive patients for treatment with betablockers. In Betablockade, ed. Mänzer, W., Schömig, A., Dietz, R. & Lichtlen, P. R. pp. 113–121. Stuttgart: G. Thieme Verlag.
Bühler, F. R., Burkart, F., Lütold, B. D., Küng, M., Marbet, G. & Pfisterer, M. (1975). Antihypertensive betablocking action as related to renin and age: a pharmacological tool to identify pathogenetic mechanisms in essential hypertension. Am. J. Cardiol., 36, 653.
Bühler, F. R., Burkart, F., Lütold, B. E., Beitel, O. & Pfisterer, M. (1977). Plasma-katecholamine und Hämodynamik im Verlauf der antihypertensiven Betablockade: verschiedene Muster bei “Propranolol-Responders” und “Non-Responders”. Schweiz. Med. Wochenschr., 107, 1590–1591.
Bühler, F. R. & Kiowski, W. (1980). Plasma catecholamines, renin, age and antihypertensive response to betablockers. In Proceedings of the Seventh International Congress of Pharmacology, ed. Vanhoutte, P. pp. 322–328. New York: Raven Press.
de Leeuw, P. W., Wester, A., Willemse, P. J. & Birkenhäger, W. H. (1980). Effects of prazosin on plasma noradrenaline and plasma renin concentration in hypertensive subjects. J. Cardiovasc. Pharmac., in press.
Distler, A., Keim, H. J., Cordes, U., Philipp, T. & Wolff, H. P. (1978). Sympathetic responsiveness and antihypertensive effect of beta receptor blockade in essential hypertension. Am. J. Med., 64, 446–451.
Esler, M. D. & Nestel, P. J. (1973). Renin and sympathetic nervous system responsiveness to adrenergic stimuli in essential hypertension. Am. J. Cardiol., 32, 643–649.
Esler, M., Zweifler, A., Randall, O. & Dequattro, V. (1977). Pathophysiologic and pharmacokinetic determinants of the antihypertensive response to propranolol. Clin. Pharmac. Ther., 22, 299–308.
Esler, M. D., Zweifler, A., Randall, O., Julius, S. & Dequattro, V. (1978). The determinants of plasma-renin activity in essential hypertension. Ann. intern. Med., 88, 746–752.
Fournier, A., Hardin, J. M., Alexandre, J. M., Lombaert, M., Ronco, G., Bezoe, J. F., Desmet, G. & Quichaud, J. (1976). Antihypertensive effect of acebutolol: its relation to sympathetic nervous system responsiveness and to plasma renin and dopamine-β-hydroxylase activities. Clin. Sci. Mol. Med., 51, 477–480(s).
Hong Tai Eng, F. W., Huber-Smith, W. & McCann, D. S. (1980). The role of sympathetic activity in normal renin essential hypertension. Hypertension, 2, 14.
Muiesan, G., Agabiti-Rosei, E., Alicandri, C. & Fariello, R. (1978). Sympathetic activity and haemodynamic changes after combined alpha- and betablockade in hypertension. In Abstract Book VIII World Congress of Cardiology, Abs. no. 1028, p. 348, 17–23 Sept. 1978, Tokyo, Japan. International Society and Federation of Cardiology.
Watson, R. D. S., Erikson, B. M., Hamilton, C. A., Reid, J. L., Stallard, T. J. & Littler, W. A. (1980). Effects of chronic beta-adrenoceptor antagonism on plasma catecholamines and blood pressure in hypertension. J. Cardiovasc. Pharmac., in press.
Author information
Authors and Affiliations
Editor information
Copyright information
© 1980 The contributors
About this chapter
Cite this chapter
Birkenhäger, W.H., de Leeuw, P.W. (1980). Does the Assay of Catecholamine Levels Contribute to the Tailoring of Antihypertensive Treatment?. In: Turner, P., Padgham, C., Hedges, A. (eds) Clinical Pharmacology & Therapeutics. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-05952-2_27
Download citation
DOI: https://doi.org/10.1007/978-1-349-05952-2_27
Publisher Name: Palgrave Macmillan, London
Print ISBN: 978-1-349-05954-6
Online ISBN: 978-1-349-05952-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)