Abstract
The observation on the decrease in dopamine(Ehringer and Hornykiewicz, 1960) and in aromatic L-amino acid decarboxylase activity with DOPA as a substrate (DOPA decarboxylase activity) (Lloyd and Hornykiewicz, 1970) in the dopaminergic regions of the parkinsonian brain indicated the disturbance in dopamine biosynthesis.
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Nagatsu, T. et al. (1981). Catecholaminergic Enzymes in Parkinson’s Disease and Related Extrapyramidal Diseases. In: Riederer, P., Usdin, E. (eds) Transmitter Biochemistry of Human Brain Tissue. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-05932-4_21
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DOI: https://doi.org/10.1007/978-1-349-05932-4_21
Publisher Name: Palgrave Macmillan, London
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