Abstract
The progress of medical science depends on the connection and cooperation of clinical observation and basic research. A success story of this cooperation is found in the understanding and treatment of Parkinson’s disease where observations in the clinic were correlated with findings of decreased dopamine (DA) concentrations in post mortem brain (Ehringer and Hornykiewicz, 1960). Animal studies first identified DA as a neurotransmitter, and further such studies were preliminary to clinical treatment with L-dopa (Birkmayer and Hornykiewicz, 1961; Barbeau et al., 1961).
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Birkmayer, W., Riederer, P. (1981). Parkinson’s Disease as a Model for Behavioural Studies in Man. In: Riederer, P., Usdin, E. (eds) Transmitter Biochemistry of Human Brain Tissue. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-05932-4_19
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DOI: https://doi.org/10.1007/978-1-349-05932-4_19
Publisher Name: Palgrave Macmillan, London
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Online ISBN: 978-1-349-05932-4
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