A radioreceptor assay for neuroleptic drugs
The routine monitoring of blood levels of drugs such as digoxin, gentamicin, lithium and anticonvulsants has been recognized as a valuable and necessary aid to clinical management. A similar approach to the control of therapy with antipsychotic, neuroleptic drugs has been complicated by (1) the large number of drugs presently in use, (2) their even larger number of active and inactive metabolites, (3) the lack of satisfactory assay procedures, and (4) a general lack of recognition of the toxic effects which may result from high dose levels.
KeywordsTardive Dyskinesia Brief Psychiatric Rate Scale Neuroleptic Drug Radioreceptor Assay Fluphenazine Decanoate
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