Biosynthesis and turnover of nicotinic acetylcholine receptors

  • Douglas M. Fambrough
Part of the Biological Council book series


In the past decade our concept of the plasma membrane has changed a great deal. In the 1960s a major concern was whether the plasma membrane should be considered as a lipid bilayer with associated proteins or a two-dimensional micellar array of ordered units. Today most students of plasma membrane structure consider this matter settled in favour of the lipid bilayer, and the overall focus of today is on the dynamic aspects of plasma membrane; the thermal motions of membrane lipid and protein molecules, the mechanisms of association of some integral and peripheral membrane proteins with the membrane, the importance of cytoskeleton-membrane interactions, and metabolic studies of the membrane constituents.


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Copyright information

© Institute of Biology Endowment Trust Fund 1981

Authors and Affiliations

  • Douglas M. Fambrough
    • 1
  1. 1.Department of EmbryologyCarnegie Institution of WashingtonBaltimoreUSA

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